Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | GFER | P55789 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1677937 | 0.84 | GAA (0.64) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL1678146 | 0.80 | SMN1; SMN2 (0.54) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL1378697 | 0.79 | NAMPT (0.48) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL975489 | 0.76 | MAPT (1.00) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL5631461 | 0.75 | F10 (0.61) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL6689700 | 0.74 | GFER (1.00) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL6139947 | 0.74 | RAB9A (0.54) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL13545926 | 0.73 | MAPT (0.53) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL6140778 | 0.73 | MAPT (0.64) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL3868815 | 0.72 | ALDH1A1 (0.48) | MEN1KMT2AMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4668614-B2 | — | — | 2011-04-13 | — | — | JP | claimed |
| JP-2006500369-A | — | — | 2006-01-05 | — | — | JP | claimed |
| EP-1558247-A1 | BENZIMIDAZOLE DERIVATIVES | MERCK PATENT GmbH (DE) | 2005-08-03 | — | — | EP | claimed |
| WO-2004017963-A1 | BENZIMIDAZOLE DERIVATIVES | MERCK PATENT GMBH (DE) | 2004-03-04 | — | — | WO | claimed |