Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMAD3 | P84022 | 1/20 | 0.58 |
| ▸ | SRC | P12931 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.51 |
| ▸ | CLK1 | P49759 | 1/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | F7 | P08709 | 1/20 | 0.47 |
| ▸ | F3 | P13726 | 1/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6049346 | 0.83 | SRC (0.47) | SRCKDM4EHPGDHSD17B10SRD5A2 | |
| SCHEMBL6138803 | 0.82 | SMAD3 (0.49) | SMAD3SRCKDM4EHPGDHSD17B10 | |
| SCHEMBL15642858 | 0.81 | PLA2G4A (0.67) | SMAD3KDM4EHPGDHSD17B10SRD5A2 | |
| SCHEMBL28763528 | 0.78 | SMAD3 (0.58) | SMAD3KDM4EHPGDHSD17B10SRD5A2 | |
| SCHEMBL7168645 | 0.78 | SMAD3 (0.63) | SMAD3SRCKDM4EHPGDHSD17B10 | |
| SCHEMBL28793315 | 0.76 | KDM4E (0.59) | SMAD3KDM4EHPGDHSD17B10SRD5A2 | |
| SCHEMBL28474583 | 0.76 | PIN1 (0.59) | SMAD3KDM4EHPGDHSD17B10SRD5A2 | |
| SCHEMBL6512147 | 0.76 | SMAD3 (0.57) | SMAD3KDM4EHPGDHSD17B10SRD5A2 | |
| SCHEMBL2421110 | 0.76 | SMAD3 (0.57) | SMAD3KDM4EHPGDHSD17B10SRD5A2 | |
| SCHEMBL14168683 | 0.76 | PIN1 (0.52) | SMAD3KDM4EHPGDHSD17B10SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311477-A4 | NOVEL THIOCARBAMIC ACID DERIVATIVES AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | PACIFIC CORP (KR) | 2005-01-12 | — | — | EP | disclosed |
| EP-1311477-A1 | NOVEL THIOCARBAMIC ACID DERIVATIVES AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | PACIFIC CORPORATION (KR) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002016317-A1 | NOVEL THIOCARBAMIC ACID DERIVATIVES AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | PACIFIC CORPORATION (KR) | 2002-02-28 | — | — | WO | disclosed |