Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 4/20 | 0.61 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.61 |
| ▸ | BCL2 | P10415 | 1/20 | 0.47 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.45 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | TYK2 | P29597 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2428547 | 0.92 | PLA2G2A (0.57) | PLA2G2APLA2G10BCL2BCL2L1TSHR | |
| SCHEMBL16584765 | 0.92 | PLA2G2A (0.59) | PLA2G2APLA2G10BCL2BCL2L1TSHR | |
| SCHEMBL6141261 | 0.87 | PARP10 (0.58) | PLA2G2APLA2G10PARP10 | |
| SCHEMBL8581956 | 0.86 | PLA2G10 (0.42) | PLA2G2APLA2G10TSHRL3MBTL1PARP10 | |
| SCHEMBL28309719 | 0.84 | CYP17A1 (0.58) | PLA2G2APLA2G10JAK2JAK1TYK2 | |
| SCHEMBL28309715 | 0.82 | F7 (0.49) | CYP3A4MAPTRECQL | |
| SCHEMBL24699358 | 0.82 | DGAT1 (0.49) | PLA2G2APLA2G10BCL2BCL2L1PARP10 | |
| SCHEMBL5802389 | 0.82 | PLA2G2A (0.46) | PLA2G2APLA2G10BCL2BCL2L1PARP10 | |
| SCHEMBL14720212 | 0.82 | PLA2G2A (0.59) | PLA2G2APLA2G10BCL2BCL2L1TSHR | |
| SCHEMBL28838076 | 0.82 | MEN1 (0.58) | PLA2G2APLA2G10BCL2BCL2L1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1497260-A1 | NOVEL METHOXYBENZAMIDE COMPOUNDS FOR USE IN MCH RECEPTOR RELATED DISORDERS | 7TM Pharma A/S (DK) | 2005-01-19 | — | — | EP | disclosed |
| WO-2004048319-A1 | NOVEL BENZAMIDE COMPOUNDS FOR USE IN MCH RECEPTOR RELATED DISORDERS | 7TM PHARMA A/S (DK) | 2004-06-10 | — | — | WO | disclosed |
| WO-2003087045-A1 | NOVEL METHOXYBENZAMIDE COMPOUNDS FOR USE IN MCH RECEPTOR RELATED DISORDERS | 7TM PHARMA A/S (DK) | 2003-10-23 | — | — | WO | disclosed |