SCHEMBL6140640

SCHEMBL6140640

CC(C)(C)Oc1ccc([S+](c2ccc(OCc3ccncc3)cc2)c2ccc(OC(C)(C)C)cc2)cc1.Cc1ccc(S(=O)(=O)[O-])c(C)c1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
RORC P51449 1/20 0.47
HSP90AA1 P07900 1/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
KMT2A Q03164 1/20 0.36
MAPK14 Q16539 1/20 0.36
HTT P42858 3/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
ADAMTS4 O75173 1/20 0.35
MMP13 P45452 1/20 0.35
LMNA P02545 2/20 0.34
ALDH1A1 P00352 1/20 0.34
NR2F2 P24468 1/20 0.34
RAB9A P51151 1/20 0.34
CYP27B1 O15528 1/20 0.34
CYP24A1 Q07973 1/20 0.34
MAOA P21397 1/20 0.34
GPR119 Q8TDV5 1/20 0.33
AR P10275 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6140028 1.00 RORC (0.47) RORCHSP90AA1MAPTHPGDKMT2A
SCHEMBL6140016 0.94 RORC (0.52) RORCHSP90AA1MAPTHPGDKMT2A
SCHEMBL6140945 0.93 RORC (0.41) RORCHSP90AA1MAPTHPGDKMT2A
SCHEMBL6140251 0.93 RORC (0.41) RORCHSP90AA1MAPTHPGDKMT2A
SCHEMBL6140238 0.89 RORC (0.44) RORCKMT2AMAPK14HTTSMN1; SMN2
SCHEMBL6140394 0.89 RORC (0.44) RORCKMT2AMAPK14HTTSMN1; SMN2
SCHEMBL6537310 0.87 RORC (0.48) RORCHSP90AA1MAPTHPGDKMT2A
SCHEMBL6140111 0.87 RORC (0.43) RORCHSP90AA1MAPTHPGDKMT2A
SCHEMBL6140502 0.85 PARP10 (0.39) KMT2AMAPK14HTTSMN1; SMN2ADAMTS4
SCHEMBL6140166 0.85 PARP10 (0.39) KMT2AMAPK14HTTSMN1; SMN2ADAMTS4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6878961-B2 Photosensitive polymeric memory elements ADVANCED MICRO DEVICES, INC. (US) 2005-04-12 US disclosed
US-20050045877-A1 PHOTOSENSITIVE POLYMERIC MEMORY ELEMENTS MORGAN STANLEY SENIOR FUNDING, INC. 2005-03-03 US disclosed
US-6825060-B1 Photosensitive polymeric memory elements ADVANCED MICRO DEVICES, INC. 2004-11-30 US disclosed
US-6534243-B1 A coating containing a cleaving compound to trim resist features; permitting a deprotection region to form within an inner portion of the patterned resist; removing coating and deprotection region to provide a second patterned feature ADVANCED MICRO DEVICES, INC. 2003-03-18 US disclosed
US-6492075-B1 COATING WITH CLEAVING COMPOUND TO CONTROLLABLY DECREASE SIZE OF DEVELOPED RESIST ADVANCED MICRO DEVICES, INC. 2002-12-10 US disclosed
US-6274289-B1 Chemical resist thickness reduction process ADVANCED MICRO DEVICES, INC. 2001-08-14 US disclosed
US-5847218-A Sulfonium salts and chemically amplified positive resist compositions SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-12-08 US disclosed