SCHEMBL6537310

SCHEMBL6537310

CCc1ccc(S(=O)(=O)[O-])cc1.Cc1ccc(S(=O)(=O)[O-])c(C)c1.c1cc(COc2ccc([S+](c3ccc(OCc4ccncc4)cc3)c3ccc(OCc4ccncc4)cc3)cc2)ccn1.c1cc(COc2ccc([S+](c3ccc(OCc4ccncc4)cc3)c3ccc(OCc4ccncc4)cc3)cc2)ccn1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RORC P51449 1/20 0.48
MAPT P10636 3/20 0.38
HSP90AA1 P07900 2/20 0.38
HPGD P15428 1/20 0.38
MAPK14 Q16539 1/20 0.37
LMNA P02545 3/20 0.37
HTT P42858 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
ADAMTS4 O75173 1/20 0.36
MMP13 P45452 1/20 0.36
ALDH1A1 P00352 1/20 0.36
NR2F2 P24468 1/20 0.36
RAB9A P51151 1/20 0.36
KMT2A Q03164 1/20 0.35
MAOB P27338 1/20 0.35
RXRA P19793 1/20 0.35
RXRB P28702 1/20 0.35
AR P10275 1/20 0.35
KDM4E B2RXH2 1/20 0.35
RECQL P46063 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6140016 0.93 RORC (0.52) RORCMAPTHSP90AA1HPGDMAPK14
SCHEMBL6140119 0.88 LMNA (0.44) RORCMAPTHSP90AA1LMNAHTT
SCHEMBL6140640 0.87 RORC (0.47) RORCMAPTHSP90AA1HPGDMAPK14
SCHEMBL6140028 0.87 RORC (0.47) RORCMAPTHSP90AA1HPGDMAPK14
SCHEMBL6140104 0.84 RORC (0.49) RORCLMNAHTTSMN1; SMN2ADAMTS4
SCHEMBL6140111 0.83 RORC (0.43) RORCMAPTHSP90AA1HPGDMAPK14
SCHEMBL6140453 0.82 NOS3 (0.45) RORCHTTSMN1; SMN2KMT2AMAOB
SCHEMBL6140251 0.81 RORC (0.41) RORCMAPTHSP90AA1HPGDKMT2A
SCHEMBL6140945 0.81 RORC (0.41) RORCMAPTHSP90AA1HPGDKMT2A
SCHEMBL6140238 0.80 RORC (0.44) RORCMAPK14LMNAHTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6825060-B1 Photosensitive polymeric memory elements ADVANCED MICRO DEVICES, INC. 2004-11-30 US disclosed