Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.32 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.32 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.32 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4519025 | 0.87 | CA14 (0.46) | CA14HDAC1HDAC2HDAC6KCNQ4 | |
| SCHEMBL30129414 | 0.86 | CA14 (0.41) | CA14HDAC1HDAC2HDAC6KCNQ4 | |
| SCHEMBL27346056 | 0.84 | CA14 (0.47) | CA14HDAC1HDAC2HDAC6KCNQ4 | |
| SCHEMBL30942676 | 0.84 | CA14 (0.40) | CA14HDAC1HDAC2HDAC6KCNQ4 | |
| SCHEMBL25969918 | 0.84 | CA14 (0.54) | CA14CA12CA1CA9MMP1 | |
| SCHEMBL1207293 | 0.84 | CA14 (0.39) | CA14HDAC1HDAC2CTSSHDAC6 | |
| SCHEMBL1143116 | 0.83 | SSTR4 (0.41) | CA14HDAC1HDAC2HDAC6KCNQ4 | |
| SCHEMBL8644916 | 0.83 | CA14 (0.40) | CA14HDAC1HDAC2HDAC6KCNQ4 | |
| SCHEMBL8644921 | 0.83 | CA14 (0.40) | CA14HDAC1HDAC2HDAC6KCNQ4 | |
| SCHEMBL3530471 | 0.83 | CA14 (0.36) | CA14CA12CA1HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6946483-B2 | Aminoalkenylbenzoyl-benzofuran or benzothiophene, method for preparing same and compositions containing same | SANOFI-AVENTIS (FR) | 2005-09-20 | — | — | US | disclosed |
| EP-1315708-B1 | AMINOALKENYLBENZOYL-BENZOFURAN OR BENZOTHIOPHENE DERIVATIVES, METHOD FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAME | SANOFI SYNTHELABO (FR) | 2004-08-11 | — | — | EP | disclosed |
| US-20030187060-A1 | Aminoalkenylbenzoyl-benzofuran or benzothiophene, method for preparing same and compositions containing same | SANOFI (FR) | 2003-10-02 | — | — | US | disclosed |
| EP-1315708-A1 | AMINOALKENYLBENZOYL-BENZOFURAN OR BENZOTHIOPHENE DERIVATIVES, METHOD FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAME | SANOFI-SYNTHELABO (FR) | 2003-06-04 | — | — | EP | disclosed |
| WO-2002016338-A1 | AMINOALKENYLBENZOYL-BENZOFURAN OR BENZOTHIOPHENE DERIVATIVES, METHOD FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAME | SANOFI-SYNTHELABO (FR) | 2002-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187060-A1 | Aminoalkenylbenzoyl-benzofuran or benzothiophene, method for preparing same and compositions containing same | ABAT, TNNT2, BCAT2 | CA14 4659/4885CA12 4356/4885CA1 4425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.