Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.49 |
| ▸ | HPN | P05981 | 1/20 | 0.44 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | PARL | Q9H300 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2859550 | 0.81 | PKM (0.80) | MAPTALDH1A1GAAPKMMAPK1 | |
| SCHEMBL6140724 | 0.76 | MGLL (0.45) | MAPTALDH1A1PKMMAPK1MEN1 | |
| SCHEMBL2557016 | 0.75 | SCN2A (0.58) | MAPTALDH1A1GAAPKMMAPK1 | |
| SCHEMBL8526316 | 0.75 | MGLL (0.59) | ALDH1A1GAAPKMMEN1KMT2A | |
| SCHEMBL10643664 | 0.73 | SCN2A (0.54) | MAPTALDH1A1GAAPKMMAPK1 | |
| SCHEMBL7549606 | 0.73 | MAPT (0.58) | MAPTALDH1A1GAAPKMMAPK1 | |
| SCHEMBL6140639 | 0.73 | MAPT (0.62) | MAPTALDH1A1GAAPKMMAPK1 | |
| SCHEMBL11592276 | 0.72 | MAPT (1.00) | MAPTALDH1A1GAAPKMMAPK1 | |
| SCHEMBL30808429 | 0.71 | MAPT (0.47) | MAPTALDH1A1GAAPKMMAPK1 | |
| SCHEMBL6140490 | 0.70 | POLB (0.57) | MAPTALDH1A1GAAPKMMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506173-A1 | METHOD FOR PRODUCING CYCLIC IMIDES IN THE PRESENCE OF POLYPHOSPHORIC ACID | MERCK PATENT GmbH (DE) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003097600-A1 | METHOD FOR PRODUCING CYCLIC IMIDES IN THE PRESENCE OF POLYPHOSPHORIC ACID | MERCK PATENT GMBH (DE) | 2003-11-27 | — | — | WO | disclosed |