Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 13/20 | 0.45 |
| ▸ | FAAH | O00519 | 5/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8526316 | 0.81 | MGLL (0.59) | MGLLFAAHHSP90AA1PKMNPSR1 | |
| SCHEMBL284697 | 0.78 | MGLL (0.75) | MGLLFAAHHSP90AA1TDP1PKM | |
| SCHEMBL6140673 | 0.76 | MAPT (0.56) | MGLLFAAHPKMMAPK1NPSR1 | |
| SCHEMBL22184048 | 0.75 | MGLL (0.38) | MGLLFAAHHSP90AA1TDP1PKM | |
| SCHEMBL6140745 | 0.71 | CA12 (0.59) | ALDH1A1LMNAKDM4EMEN1MAPT | |
| SCHEMBL22916838 | 0.70 | MGLL (0.45) | MGLLFAAHHSP90AA1TDP1PKM | |
| SCHEMBL721079 | 0.68 | KMT2A (0.64) | TDP1NPSR1ALDH1A1LMNAKDM4E | |
| SCHEMBL1740441 | 0.68 | MGLL (0.63) | MGLLFAAHHSP90AA1TDP1PKM | |
| 4,4'-Methylenedianiline SCHEMBL7738791 | 0.68 | MGLL (0.81) | MGLLFAAHHSP90AA1TDP1PKM | |
| SCHEMBL19844745 | 0.68 | MGLL (0.81) | MGLLFAAHHSP90AA1TDP1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506173-A1 | METHOD FOR PRODUCING CYCLIC IMIDES IN THE PRESENCE OF POLYPHOSPHORIC ACID | MERCK PATENT GmbH (DE) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003097600-A1 | METHOD FOR PRODUCING CYCLIC IMIDES IN THE PRESENCE OF POLYPHOSPHORIC ACID | MERCK PATENT GMBH (DE) | 2003-11-27 | — | — | WO | disclosed |