Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23270137 | 0.80 | MAOA (0.44) | MAOAMAOBKDM1ASLC6A3OPRL1 | |
| SCHEMBL3719123 | 0.80 | CYP1A2 (0.47) | MAOAMAOBKDM1ASLC6A3OPRL1 | |
| SCHEMBL6141468 | 0.77 | MAOB (0.39) | MAOAMAOBSLC6A3DAOSLC6A4 | |
| SCHEMBL6140620 | 0.76 | SLC6A4 (0.45) | SLC6A3SLC6A4SLC6A2PIM1PIM2 | |
| SCHEMBL626219 | 0.73 | SLC6A3 (0.45) | MAOAMAOBKDM1ASLC6A3OPRL1 | |
| SCHEMBL3158074 | 0.73 | SLC6A3 (0.49) | MAOAMAOBKDM1ASLC6A3OPRL1 | |
| SCHEMBL3396912 | 0.72 | OPRM1 (0.46) | MAOAMAOBSLC6A3OPRL1OPRM1 | |
| SCHEMBL3516067 | 0.72 | SLC6A3 (0.51) | MAOAMAOBKDM1ASLC6A3OPRL1 | |
| SCHEMBL31441140 | 0.72 | SLC6A3 (0.51) | MAOAMAOBKDM1ASLC6A3OPRL1 | |
| SCHEMBL31441151 | 0.72 | SLC6A3 (0.51) | MAOAMAOBKDM1ASLC6A3OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2061790-B1 | Substituted aminopyrazolopyridines and salts thereof, their preparations and pharmaceutical compositions comprising them | BAYER IP GMBH (DE) | 2014-08-13 | — | — | EP | disclosed |
| EP-1517881-A1 | 4-(3,3-DIHALO-ALLYLOXY)PHENOXY ALKYL DERIVATIVES | Syngenta Participations AG (CH) | 2005-03-30 | — | — | EP | disclosed |
| WO-2004002943-A1 | 4-(3,3-DIHALO-ALLYLOXY)PHENOXY ALKYL DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-01-08 | — | — | WO | disclosed |