Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 19/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5620624 | 0.81 | PTGER1 (0.64) | PTGER1CYP2C9 | |
| SCHEMBL5619871 | 0.81 | PTGER1 (0.62) | PTGER1CYP2C9 | |
| SCHEMBL5621101 | 0.80 | PTGER1 (0.67) | PTGER1CYP2C9 | |
| SCHEMBL14499132 | 0.80 | PTGER1 (1.00) | PTGER1CYP2C9 | |
| SCHEMBL5620567 | 0.79 | PTGER1 (0.66) | PTGER1CYP2C9 | |
| SCHEMBL24732325 | 0.76 | KMO (0.61) | PTGER1CYP2C9MCL1 | |
| SCHEMBL5620526 | 0.72 | PTGER1 (0.60) | PTGER1CYP2C9 | |
| SCHEMBL6140486 | 0.71 | PTGER1 (0.84) | PTGER1CYP2C9 | |
| SCHEMBL28839717 | 0.70 | BACE1 (0.56) | MCL1 | |
| SCHEMBL659462 | 0.69 | HSD17B10 (0.70) | CYP2C9MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7232821-B2 | (2-((2-alkoxy)-phenyl) -cyclopent-1enyl) aromatic carbo and heterocyclic acid and derivatives | GLAXO GROUP LIMITED (GB) | 2007-06-19 | — | — | US | disclosed |
| US-7232821-B2 | (2-((2-alkoxy)-phenyl) -cyclopent-1enyl) aromatic carbo and heterocyclic acid and derivatives | GLAXO GROUP LIMITED (GB) | 2007-06-19 | — | — | US | disclosed |
| EP-1492757-A1 | (2-((2-ALKOXY)-PHENYL)-CYCLOPENT-1-ENYL) AROMATIC CARBO- AND HETEROCYCLIC CARBOXYLIC ACID AND DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2005-01-05 | — | — | EP | disclosed |
| WO-2003084917-A1 | (2-((2-ALKOXY) -PHENYL) -CYCLOPENT-1-ENYL) AROMATIC CARBO AND HETEROCYCLIC ACID AND DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2003-10-16 | — | — | WO | disclosed |