Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 10/20 | 0.44 |
| ▸ | ITGAV | P06756 | 2/20 | 0.44 |
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 8/20 | 0.38 |
| ▸ | ITGB7 | P26010 | 6/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | CPA1 | P15085 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6142370 | 0.83 | ITGB1 (0.66) | ITGB1ITGAVITGA4ITGB7FFAR1 | |
| SCHEMBL3319945 | 0.78 | GRIA2 (0.49) | — | |
| SCHEMBL6151313 | 0.77 | ITGB1 (0.52) | ITGB1ITGAVITGA4ITGB7 | |
| SCHEMBL3314241 | 0.77 | ITGB1 (0.70) | ITGB1ITGAVITGA4ITGB7 | |
| Hydrochloric Acid SCHEMBL3313215 | 0.77 | GRIA2 (0.48) | — | |
| SCHEMBL6140931 | 0.75 | ITGB1 (0.54) | ITGB1ITGAVITGA4ITGB7 | |
| SCHEMBL4627756 | 0.74 | ITGB1 (0.54) | ITGB1ITGAVITGA4ITGB7MME | |
| SCHEMBL6140590 | 0.73 | ITGB1 (0.56) | ITGB1ITGAVFABP4ITGA4ITGB7 | |
| SCHEMBL4625235 | 0.70 | ITGB1 (0.56) | ITGB1ITGAVITGA4ITGB7 | |
| SCHEMBL3315065 | 0.70 | FABP3 (0.42) | FABP3FABP4FABP5FFAR1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501801-A1 | 2,6-QUINOLINYL AND 2,6-NAPHTHYL DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES AS VLA-4 INHIBITORS | UCB, S.A. (BE) | 2005-02-02 | — | — | EP | disclosed |
| WO-2003093237-A1 | 2,6-QUINOLINYL AND 2,6-NAPHTHYL DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES AS VLA-4 INHIBITORS | UCB, S.A. (BE) | 2003-11-13 | — | — | WO | disclosed |