Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31459475 | 0.79 | ADRA1A (0.41) | HDAC4GRIN1GRIN2ASLC6A4GRIN2D | |
| SCHEMBL4555845 | 0.79 | ADRA1A (0.41) | HDAC4GRIN1GRIN2ASLC6A4GRIN2D | |
| SCHEMBL3863243 | 0.77 | HDAC4 (0.44) | HDAC4OPRK1OPRM1HDAC3HDAC1 | |
| SCHEMBL6141377 | 0.76 | SLC6A3 (0.45) | SLC6A4TSHRPDE7AAHR | |
| SCHEMBL8747130 | 0.72 | HDAC4 (0.45) | HDAC4GRIN1GRIN2ASLC6A4GRIN2D | |
| SCHEMBL18742441 | 0.72 | HDAC4 (0.41) | HDAC4GRIN1GRIN2ASLC6A4GRIN2D | |
| SCHEMBL2288498 | 0.71 | ADRA1A (0.42) | HDAC4GRIN1GRIN2ASLC6A4GRIN2D | |
| SCHEMBL11993802 | 0.69 | HDAC4 (0.44) | HDAC4GRIN1GRIN2ASLC6A4GRIN2D | |
| SCHEMBL324341 | 0.69 | MEN1 (0.41) | OPRK1OPRM1TAAR1 | |
| SCHEMBL28689514 | 0.68 | SCD (0.40) | HDAC4OPRM1CRHBPCRHR2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1517881-A1 | 4-(3,3-DIHALO-ALLYLOXY)PHENOXY ALKYL DERIVATIVES | Syngenta Participations AG (CH) | 2005-03-30 | — | — | EP | disclosed |
| WO-2004002943-A1 | 4-(3,3-DIHALO-ALLYLOXY)PHENOXY ALKYL DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-01-08 | — | — | WO | disclosed |