Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LSS | P48449 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4853715 | 0.79 | ALDH1A1 (0.60) | ADRB2ADRB1ALDH1A1KDM4EMEN1 | |
| SCHEMBL4852503 | 0.79 | ALDH1A1 (0.60) | ADRB2ADRB1ALDH1A1KDM4EMEN1 | |
| SCHEMBL5915596 | 0.78 | TAAR1 (0.49) | USP2ALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL6983619 | 0.76 | MAPT (0.46) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL6141669 | 0.73 | TAAR1 (0.60) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL13037433 | 0.70 | TAAR1 (0.50) | USP2ALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL8175589 | 0.70 | KDM4E (0.48) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL4849767 | 0.68 | KDM4E (0.47) | ADRB2ADRB1ALDH1A1KDM4EMEN1 | |
| SCHEMBL4849200 | 0.68 | KDM4E (0.47) | ADRB2ADRB1ALDH1A1KDM4EMEN1 | |
| SCHEMBL3221593 | 0.67 | MEN1 (0.44) | ALDH1A1KDM4EMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1515940-A2 | AMINOALKOXY-FUNCTIONAL CHALCONES | Lica Pharmaceuticals A/S (DK) | 2005-03-23 | — | — | EP | disclosed |
| WO-2003097574-A2 | AMINOALKOXY-FUNCTIONAL CHALCONES | LICA PHARMACEUTICALS A/S (DK) | 2003-11-27 | — | — | WO | disclosed |