Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ERN1 | O75460 | 4/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6141669 | 0.94 | TAAR1 (0.60) | TAAR1ALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL13037433 | 0.89 | TAAR1 (0.50) | TAAR1ALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL6983619 | 0.79 | MAPT (0.46) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL8175589 | 0.78 | KDM4E (0.48) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL6141027 | 0.78 | ADRB2 (0.42) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL29957257 | 0.77 | LMNA (0.48) | ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL3150352 | 0.77 | LMNA (0.48) | ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL6128189 | 0.75 | SLC6A4 (0.41) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL3221593 | 0.75 | MEN1 (0.44) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL7379036 | 0.74 | TAAR1 (0.41) | TAAR1ALDH1A1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060052600-A1 | Amino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2006-03-09 | — | — | US | disclosed |