SCHEMBL6141510

SCHEMBL6141510

O=C(O)C=CCC1CC(=O)O1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRR1 P24046 2/20 0.35
GABRR2 P28476 2/20 0.35
BLM P54132 2/20 0.35
LMNA P02545 2/20 0.35
TSHR P16473 2/20 0.35
APEX1 P27695 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
GABRR3 A8MPY1 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
SLC22A12 Q96S37 6/20 0.34
KDM4E B2RXH2 5/20 0.33
ALDH1A1 P00352 3/20 0.33
GAA P10253 3/20 0.33
MPI P34949 1/20 0.33
APOBEC3G Q9HC16 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 2/20 0.32
GLA P06280 2/20 0.32
HCAR2 Q8TDS4 1/20 0.32
MEN1 O00255 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1469682 0.75
SCHEMBL9063425 0.69 ITGB1 (0.52) GABRR1GABRR2BLMLMNATSHR
SCHEMBL1414793 0.69
SCHEMBL3269504 0.68 ALDH1A1 (0.42) LMNAKDM4EALDH1A1SMN1; SMN2MEN1
SCHEMBL27687037 0.67 MGLL (0.39) LMNAALDH1A1SMN1; SMN2POLBHPGD
SCHEMBL16650833 0.67 GABRR1 (0.33) GABRR1GABRR2BLMLMNATSHR
SCHEMBL3654343 0.66
SCHEMBL3654341 0.66
SCHEMBL4438931 0.66 ALDH1A1 (0.63) BLMLMNATSHRAPEX1NPSR1
SCHEMBL20617554 0.65 HTT (0.46) LMNANPSR1KDM4ESMN1; SMN2ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1553452-A2 Photoresist compositions comprising polymers Rohm and Haas Electronic Materials, L.L.C. (US) 2005-07-13 EP disclosed
US-20050142486-A1 Polymers and photoresist compositions comprising same Corless, Peter (US) 2005-06-30 US disclosed