Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR2 | P30874 | 3/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5218328 | 0.78 | PTGDR2 (0.48) | CHEK1CHRNB4CHRNA3CHEK2MKNK1 | |
| SCHEMBL4854885 | 0.77 | TDP1 (0.56) | KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL11466925 | 0.77 | CHRNB4 (0.54) | CHRNB4CHRNA3ALDH1A1CHRNB2CHRNA4 | |
| SCHEMBL6110644 | 0.76 | LTA4H (0.53) | SSTR2CHEK2 | |
| SCHEMBL4849189 | 0.75 | CYP2D6 (0.53) | KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL5701841 | 0.75 | KDM4E (0.42) | CHRNB4CHRNA3KDM4EMEN1ALDH1A1 | |
| SCHEMBL4856576 | 0.74 | CYP2D6 (0.52) | KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL4845580 | 0.74 | SLC6A9 (0.49) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL11457727 | 0.73 | PIM1 (0.49) | SSTR2CHRNB4CHRNA3KMT2ACHRNB2 | |
| SCHEMBL4852186 | 0.73 | SLC6A9 (0.46) | KDM4EMEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1515940-A2 | AMINOALKOXY-FUNCTIONAL CHALCONES | Lica Pharmaceuticals A/S (DK) | 2005-03-23 | — | — | EP | disclosed |
| WO-2003097574-A2 | AMINOALKOXY-FUNCTIONAL CHALCONES | LICA PHARMACEUTICALS A/S (DK) | 2003-11-27 | — | — | WO | disclosed |