Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 5/20 | 0.43 |
| ▸ | IGF1R | P08069 | 4/20 | 0.43 |
| ▸ | BPTF | Q12830 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | FCGR3B | O75015 | 1/20 | 0.35 |
| ▸ | FCGR1A | P12314 | 1/20 | 0.35 |
| ▸ | FCGR2A | P12318 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2991367 | 0.99 | MAOA (0.42) | CYP19A1EGFRIGF1RBPTFMAOA | |
| SCHEMBL6141834 | 0.88 | MITF (0.35) | CYP19A1EGFRIGF1RBPTFABCB1 | |
| Hydrochloric Acid SCHEMBL2996463 | 0.87 | MITF (0.34) | CYP19A1EGFRIGF1RMAOAMAOB | |
| SCHEMBL6141854 | 0.86 | MITF (0.44) | CYP19A1EGFRMAOAMAOBAURKA | |
| Hydrochloric Acid SCHEMBL2993538 | 0.85 | MITF (0.43) | CYP19A1EGFRMAOAMAOBAURKA | |
| SCHEMBL7563743 | 0.82 | ALDH1A1 (0.44) | TDO2 | |
| SCHEMBL6272601 | 0.80 | MITF (0.33) | — | |
| SCHEMBL6141596 | 0.79 | CA12 (0.37) | EGFR | |
| SCHEMBL6304195 | 0.79 | KDM4C (0.40) | — | |
| Hydrochloric Acid SCHEMBL6740843 | 0.79 | PRSS1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1493731-A1 | N-benzyl-p-phenylenediamine-derivatives containing colouring agents for keratin fibres and these derivatives | Wella Aktiengesellschaft (DE) | 2005-01-05 | — | — | EP | disclosed |