Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 6/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 6/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 6/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 6/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5519457 | 0.85 | ALOX15 (0.40) | ALOX15SLC7A5CA12CA1CA2 | |
| SCHEMBL27570249 | 0.85 | ALOX15 (0.40) | ALOX15SLC7A5CA12CA1CA2 | |
| SCHEMBL2215365 | 0.84 | HTT (0.42) | ALOX15SLC7A5CA12CA1CA2 | |
| SCHEMBL26622785 | 0.84 | ALOX15 (0.40) | ALOX15SLC7A5CA12CA1CA2 | |
| SCHEMBL13574670 | 0.84 | CA12 (0.37) | ALOX15SLC7A5CA12CA1CA2 | |
| SCHEMBL27516326 | 0.83 | GABRA1 (0.38) | ALOX15SLC7A5CA12CA1CA2 | |
| SCHEMBL31705858 | 0.81 | KDM4E (0.51) | ALOX15CA12CA1CA2CA9 | |
| SCHEMBL41129 | 0.81 | KDM4E (0.51) | ALOX15CA12CA1CA2CA9 | |
| SCHEMBL28771015 | 0.78 | SLC7A5 (0.34) | ALOX15SLC7A5CA12CA1CA2 | |
| SCHEMBL710842 | 0.77 | CYP2C9 (0.53) | ALOX15CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1199306-B1 | BIARYLUREA DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2005-12-07 | — | — | EP | disclosed |
| US-6958333-B1 | Biarylurea derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2005-10-25 | — | — | US | disclosed |
| EP-1557168-A2 | Biarylurea Derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2005-07-27 | — | — | EP | disclosed |
| EP-1199306-A1 | BIARYLUREA DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2002-04-24 | — | — | EP | disclosed |