Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.58 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NOS1 | P29475 | 1/20 | 0.45 |
| ▸ | NOS2 | P35228 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15568242 | 0.82 | KMT2A (0.53) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL11956181 | 0.82 | CHRNB2 (0.63) | CHRNB2CHRNA4KDM4EALDH1A1LMNA | |
| SCHEMBL3030411 | 0.81 | CYP2D6 (0.53) | — | |
| SCHEMBL185250 | 0.81 | CHRNB2 (0.66) | CHRNB2CHRNA4KDM4EALDH1A1LMNA | |
| SCHEMBL781665 | 0.81 | KEAP1 (0.70) | CHRNB2CHRNA4KDM4EALDH1A1LMNA | |
| SCHEMBL6588597 | 0.80 | HRH3 (0.66) | KDM4EALDH1A1LTA4HESR1KEAP1 | |
| SCHEMBL901802 | 0.79 | CHRNB2 (0.59) | CHRNB2CHRNA4KDM4EALDH1A1LMNA | |
| SCHEMBL11245203 | 0.79 | LTA4H (0.59) | CHRNB2CHRNA4KDM4EALDH1A1LMNA | |
| SCHEMBL29658517 | 0.79 | CHRNB2 (0.59) | CHRNB2CHRNA4KDM4EALDH1A1LMNA | |
| SCHEMBL14418361 | 0.79 | CHRNB2 (0.55) | CHRNB2CHRNA4KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1515940-A2 | AMINOALKOXY-FUNCTIONAL CHALCONES | Lica Pharmaceuticals A/S (DK) | 2005-03-23 | — | — | EP | disclosed |
| WO-2003097574-A2 | AMINOALKOXY-FUNCTIONAL CHALCONES | LICA PHARMACEUTICALS A/S (DK) | 2003-11-27 | — | — | WO | disclosed |