Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.87 |
| ▸ | TSHR | P16473 | 4/20 | 0.87 |
| ▸ | LMNA | P02545 | 2/20 | 0.87 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.87 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.87 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.87 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.87 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.87 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.87 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.87 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.70 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.70 |
| ▸ | KDR | P35968 | 1/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.64 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butylparaben SCHEMBL23458813 | 0.95 | ESR1 (0.79) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| Hexyl 4-Hydroxybenzoate SCHEMBL28929472 | 0.94 | TSHR (0.77) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| Butylparaben SCHEMBL28872721 | 0.93 | ESR1 (0.93) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| Butylparaben SCHEMBL5789201 | 0.93 | ESR1 (1.00) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL37477 | 0.93 | TSHR (0.74) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| Butylparaben SCHEMBL3647 | 0.93 | ESR1 (1.00) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| Terephthalic Acid SCHEMBL21044732 | 0.93 | TSHR (0.74) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| Butylparaben SCHEMBL9172319 | 0.92 | ESR1 (0.96) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| Butylparaben SCHEMBL761983 | 0.92 | ESR1 (0.96) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| Butylparaben SCHEMBL2325184 | 0.92 | ESR1 (0.96) | ESR1TSHRLMNACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107635589-B | Essentially antimicrobial porous matrix composites and methods of making the same | 约翰·保罗·威尔逊 | 2020-07-17 | — | — | CN | disclosed |
| CN-103415531-B | For treating the peptide of skin disorder | 器官平衡有限责任公司 | 2016-10-26 | — | — | CN | disclosed |
| CN-101309707-A | Composition comprising lipoxygenase inhibitor and cyclodextrin | BAXTER INT (US) | 2008-11-19 | — | — | CN | disclosed |
| US-20050271692-A1 | Topical cosmetic compositions | COSMECEUTIC SOLUTIONS PTY. LTD. | 2005-12-08 | — | — | US | disclosed |
| EP-1534214-A1 | TOPICAL COSMETIC COMPOSITIONS | Cosmeceutic Solutions Pty Ltd (AU) | 2005-06-01 | — | — | EP | disclosed |
| WO-2004000242-A1 | TOPICAL COSMETIC COMPOSITIONS | COSMECEUTIC SOLUTIONS PTY LTD (AU) | 2003-12-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050271692-A1 | Topical cosmetic compositions | CUTA, MITF, DSG1 | ESR1 1257/4885TSHR 2861/4885LMNA 1599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.