Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MPI | P34949 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7095603 | 0.80 | CYP2C9 (0.45) | CYP2C9LMNAHPGDKDM4EALDH1A1 | |
| SCHEMBL5362668 | 0.79 | CYP2C9 (0.47) | CYP2C9LMNAHPGDKDM4EALDH1A1 | |
| SCHEMBL16835711 | 0.74 | CYP2C9 (0.45) | CYP2C9LMNAHPGDKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL4620930 | 0.66 | MAPT (0.31) | CYP2C9LMNAKDM4EMAPT | |
| SCHEMBL13376542 | 0.65 | CYP2C9 (0.57) | CYP2C9LMNAHPGDKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL6142137 | 0.65 | ALDH1A1 (0.39) | CYP2C9LMNAHPGDKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL16654018 | 0.64 | POLB (0.31) | KDM4EPOLB | |
| SCHEMBL5349583 | 0.64 | DHODH (0.44) | CYP2C9LMNAHPGDKDM4EALDH1A1 | |
| SCHEMBL7053846 | 0.63 | POLB (0.33) | POLB | |
| Hydrochloric Acid SCHEMBL4620650 | 0.63 | ALDH1A1 (0.35) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1492746-A1 | SELECTIVE COUPLING OF TERMINAL OLEFINS WITH ETHYLENE TO MANUFACTURE LINEAR ALPHA-OLEFINS | ExxonMobil Research and Engineering Company (US) | 2005-01-05 | — | — | EP | claimed |
| WO-2003072529-A1 | SELECTIVE COUPLING OF TERMINAL OLEFINS WITH ETHYLENE TO MANUFACTURE LINEAR ALPHA-OLEFINS | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2003-09-04 | — | — | WO | claimed |