SCHEMBL6142173

SCHEMBL6142173

O=S(=O)(O)c1[c]cc(O)c(S(=O)(=O)O)c1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.40
LMNA P02545 2/20 0.40
HPGD P15428 1/20 0.40
HIF1A Q16665 1/20 0.40
EGFR P00533 1/20 0.35
NSD2 O96028 1/20 0.31
MMP14 P50281 1/20 0.31
CASP6 P55212 1/20 0.31
MPL P40238 1/20 0.31
ALDH1A1 P00352 2/20 0.31
CASP1 P29466 1/20 0.31
CASP7 P55210 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
PTGS1 P23219 1/20 0.31
NQO1 P15559 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6632285 0.83 ALDH1A1 (0.32) HSD17B10LMNAALDH1A1
SCHEMBL6633299 0.83 LMNA (0.31) HSD17B10LMNAHPGDHIF1A
SCHEMBL6631408 0.81 HSD17B10 (0.37) HSD17B10LMNAHPGDHIF1AEGFR
SCHEMBL9169863 0.78 HSD17B10 (0.39) HSD17B10LMNAHPGDHIF1AEGFR
SCHEMBL10646743 0.78 TTR (0.36) HSD17B10NSD2CASP6ALDH1A1CASP1
SCHEMBL10508320 0.78 BRD4 (0.36) HSD17B10LMNAHPGDHIF1A
SCHEMBL4409480 0.75 TTR (0.37) HSD17B10HPGDNSD2CASP6ALDH1A1
SCHEMBL5049711 0.73 BRD4 (0.39)
SCHEMBL9169853 0.73 TSHR (0.34) HSD17B10HPGDALDH1A1TDP1
SCHEMBL9167903 0.73 BRD4 (0.33) HSD17B10HPGDHIF1AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1492493-A1 METHOD FOR THE GENERATION OF MEMORY EFFECTS ON HAIR Mnemoscience GmbH (DE) 2005-01-05 EP disclosed
WO-2003084490-A1 METHOD FOR THE GENERATION OF MEMORY EFFECTS ON HAIR MNEMOSCIENCE GMBH (DE) 2003-10-16 WO disclosed
US-5792879-A OXIDIZING LEUCO COMPOUND IN PRESENCE OF DILUENT AND HEAVY METAL COMPLEX OXYGEN TRANSFER CATALYST WITH HYDROGEN PEROXIDE, ORGANIC HYDROPEROXIDE OR PERCARBOXYLIC ACID BASF AKTIENGESELLSCHAFT (DE) 1998-08-11 US disclosed
US-5659053-A REACTING A LEUCO COMPOUND WITH HYDROGEN PEROXIDE USING AN OXYGEN TRANSFER CATALYST IN THE PRESENCE OF A DILUENT AND THE ABSENCE OF CHLORANIL BASF AKTIENGESELLSCHAFT (DE) 1997-08-19 US disclosed
EP-0568806-B1 Method for producing diarylmethane or triarylmethane dyestuffs by oxidation BASF AG (DE) 1997-06-11 EP disclosed
EP-0564930-B1 Method of preparing diaryl or triaryl methane dyes BASF AG (DE) 1997-02-12 EP disclosed
US-5347022-A Oxidation of di- or triarylmethanes BASF AKTIENGESELLSCHAFT (DE) 1994-09-13 US disclosed
EP-0568806-A1 Method for producing diarylmethane or triarylmethane dyestuffs by oxidation BASF Aktiengesellschaft (DE) 1993-11-10 EP disclosed
EP-0564930-A1 Method of preparing diaryl or triaryl methane dyes BASF Aktiengesellschaft (DE) 1993-10-13 EP disclosed