SCHEMBL6142502

SCHEMBL6142502

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nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.46
LMNA P02545 2/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
PDE4A P27815 1/20 0.41
USP2 O75604 1/20 0.38
SLCO1B1 Q9Y6L6 1/20 0.38
KDM4E B2RXH2 2/20 0.36
TSHR P16473 2/20 0.34
CHRM2 P08172 1/20 0.34
CHRM4 P08173 1/20 0.34
CHRM1 P11229 1/20 0.34
TBXA2R P21731 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
GALR3 O60755 1/20 0.33
MAPT P10636 1/20 0.33
BLM P54132 1/20 0.33
ALOX15 P16050 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18451403 0.98 LMNA (0.44) TDP1LMNAL3MBTL1PDE4AUSP2
SCHEMBL3289378 0.87 PDE4A (0.48) TDP1LMNAL3MBTL1PDE4AUSP2
SCHEMBL1656749 0.85 PDE4A (0.50) TDP1LMNAL3MBTL1PDE4AUSP2
SCHEMBL396999 0.84 TSHR (0.39) TDP1LMNAL3MBTL1PDE4AUSP2
Potassium Ion SCHEMBL3187155 0.83 LMNA (0.50) TDP1LMNAL3MBTL1PDE4AUSP2
SCHEMBL15267779 0.83 TDP1 (0.35) TDP1LMNAL3MBTL1PDE4ATSHR
SCHEMBL4115003 0.82 LMNA (0.48) TDP1LMNAL3MBTL1PDE4AUSP2
Methane SCHEMBL27945359 0.82 TSHR (0.37) TDP1LMNAL3MBTL1PDE4ATSHR
SCHEMBL16341810 0.81 LMNA (0.35) TDP1LMNAL3MBTL1PDE4AUSP2
SCHEMBL17443328 0.80 LMNA (0.39) TDP1LMNAL3MBTL1PDE4AUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6852193-B2 Semi-solid one- or two-part compositions LOCTITE (R&D) LIMITED (IE) 2005-02-08 US disclosed
EP-1286786-B1 APPLICATOR PACKS FOR USE WITH SPREADABLE ADHESIVE COMPOSITIONS LOCTITE R & D LTD (IE) 2005-01-12 EP disclosed
US-6828291-B2 Semi-solid compositions for removing cured product LOCTITE (R&D) LIMITED (IE) 2004-12-07 US disclosed
US-20030172987-A1 Spreadable adhesive compositions and applicators for use therewith LOCTITE (IRELAND)LIMITED (IE) 2003-09-18 US disclosed
US-20030171467-A1 Semi-solid one- or two-part compositions LOCTITE (R&D) LIMITED (IE) 2003-09-11 US disclosed
US-20030164222-A1 Semi-solid primer compositions LOCTITE (R&D) LIMITED (IE) 2003-09-04 US disclosed
US-20030130150-A1 Semi- solid compositions for removing cured product LOCTITE (R&D) LIMITED (IE) 2003-07-10 US disclosed
EP-1286786-A2 SPREADABLE ADHESIVE COMPOSITIONS AND APPLICATORS FOR USE THEREWITH Loctite (R & D) Limited (IE) 2003-03-05 EP disclosed
WO-2001092435-A1 SEMI-SOLID PRIMER COMPOSITIONS LOCTITE (R & D) LIMITED (IE) 2001-12-06 WO disclosed
WO-2001091915-A2 SPREADABLE ADHESIVE COMPOSITIONS AND APPLICATORS FOR USE THEREWITH LOCTITE (R & D) LIMITED (IE) 2001-12-06 WO disclosed
WO-2001092430-A1 SEMI-SOLID COMPOSITIONS FOR REMOVING CURED PRODUCT LOCTITE (R & D) LIMITED (IE) 2001-12-06 WO disclosed
WO-2001092434-A1 SEMI-SOLID ONE- OR TWO-PART COMPOSITIONS LOCTITE (R & D) LIMITED (IE) 2001-12-06 WO disclosed