Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1656749 | 0.98 | PDE4A (0.50) | PDE4AUSP2SLCO1B1TDP1LMNA | |
| SCHEMBL6142502 | 0.87 | TDP1 (0.46) | PDE4AUSP2SLCO1B1TDP1LMNA | |
| SCHEMBL18451403 | 0.85 | LMNA (0.44) | PDE4AUSP2SLCO1B1TDP1LMNA | |
| SCHEMBL9539845 | 0.84 | PDE4A (0.40) | PDE4AUSP2SLCO1B1TDP1LMNA | |
| SCHEMBL8465610 | 0.82 | PDE4A (0.54) | PDE4AUSP2SLCO1B1TDP1LMNA | |
| Potassium Ion SCHEMBL3187155 | 0.81 | LMNA (0.50) | PDE4AUSP2SLCO1B1TDP1LMNA | |
| SCHEMBL8680823 | 0.81 | PDE4A (0.52) | PDE4AUSP2SLCO1B1TDP1LMNA | |
| SCHEMBL6274785 | 0.81 | PDE4A (0.52) | PDE4AUSP2SLCO1B1TDP1LMNA | |
| SCHEMBL15049970 | 0.81 | PDE4A (0.52) | PDE4AUSP2SLCO1B1TDP1LMNA | |
| SCHEMBL7994016 | 0.80 | PDE4A (0.57) | PDE4AUSP2SLCO1B1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1536843-B1 | RADIOLABELED COMPOUNDS AND LIPOSOMES AND THEIR METHODS OF MAKING AND USING THE SAME | UNIV TEXAS (US) | 2010-12-22 | — | — | EP | disclosed |
| US-7718160-B2 | Radiolabeled compounds and liposomes and their method of making and using same | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2010-05-18 | — | — | US | disclosed |
| EP-1536843-A4 | RADIOLABELED COMPOUNDS AND LIPOSOMES AND THEIR METHODS OF MAKING AND USING THE SAME | UNIV TEXAS (US) | 2009-01-14 | — | — | EP | disclosed |
| US-20050222396-A1 | Radiolabeled compounds and liposomes and their method of making and using same | PLUS THERAPEUTICS, INC. | 2005-10-06 | — | — | US | disclosed |
| EP-1536843-A2 | RADIOLABELED COMPOUNDS AND LIPOSOMES AND THEIR METHODS OF MAKING AND USING THE SAME | BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM (US) | 2005-06-08 | — | — | EP | disclosed |
| WO-2004004635-A2 | RADIOLABELED COMPOUNDS AND LIPOSOMES AND THEIR METHODS OF MAKING AND USING THE SAME | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2004-01-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222396-A1 | Radiolabeled compounds and liposomes and their method of making and using same | LIPA, NPC1L1, GBA1 | PDE4A 1089/4885USP2 1301/4885SLCO1B1 208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.