Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18451403 | 0.85 | LMNA (0.44) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL6142502 | 0.83 | TDP1 (0.46) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL1656749 | 0.83 | PDE4A (0.50) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL3289378 | 0.81 | PDE4A (0.48) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL3386184 | 0.81 | LMNA (0.50) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| Potassium Ion SCHEMBL9419061 | 0.80 | LMNA (0.48) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL6267186 | 0.79 | LMNA (0.62) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL3385393 | 0.79 | LMNA (0.47) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL17443328 | 0.79 | LMNA (0.39) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| Lithium Ion SCHEMBL10340066 | 0.78 | LMNA (0.50) | LMNAL3MBTL1PDE4ATDP1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7655153-B2 | Deicer compositions including corrosion inhibitors for galvanized metal | CARGILL, INCORPORATED (US) | 2010-02-02 | — | — | US | disclosed |
| WO-2008054663-A1 | DEICER COMPOSITIONS INCLUDING CORROSION INHIBITORS FOR GALVANIZED METAL | CARGILL, INCORPORATED (US) | 2008-05-08 | — | — | WO | disclosed |
| US-20080099716-A1 | Deicer compositions including corrosion inhibitors for galvanized metal | CARGILL, INCORPORATED | 2008-05-01 | — | — | US | disclosed |