Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1012291 | 0.75 | CES2 (0.39) | CES2CES1RAPGEF4 | |
| SCHEMBL12621 | 0.65 | RAPGEF4 (0.52) | CES2CES1RAPGEF4 | |
| SCHEMBL1547507 | 0.65 | TUBB1 (0.42) | CES2CES1RAPGEF4 | |
| SCHEMBL1525706 | 0.63 | CES2 (0.45) | CES2CES1RAPGEF4 | |
| SCHEMBL531337 | 0.63 | CES2 (0.52) | CES2CES1RAPGEF4 | |
| Chloromethane SCHEMBL27844640 | 0.63 | CES2 (0.46) | CES2CES1RAPGEF4 | |
| Ethane SCHEMBL27965993 | 0.61 | CA1 (0.45) | CES2CES1RAPGEF4 | |
| SCHEMBL2096366 | 0.60 | CES2 (0.43) | CES2CES1RAPGEF4 | |
| SCHEMBL3947336 | 0.59 | MEN1 (0.41) | CES2CES1RAPGEF4 | |
| SCHEMBL1998090 | 0.59 | ALDH1A1 (0.56) | CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1034196-B1 | CATALYST AND METHODS FOR POLYMERIZING CYCLOOLEFINS | PROMERUS LLC (US) | 2005-01-12 | — | — | EP | claimed |
| EP-0827962-B1 | Preparation of silylium salts | DOW CHEMICAL CO (US) | 2001-01-10 | — | — | EP | claimed |
| EP-0781299-B1 | SILYLIUM CATIONIC POLYMERIZATION ACTIVATORS FOR METALLOCENE COMPLEXES | DOW CHEMICAL CO (US) | 1998-09-09 | — | — | EP | claimed |