Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 3/20 | 0.56 |
| ▸ | COPS5 | Q92905 | 2/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | STAMBP | O95630 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL841789 | 0.90 | — | — | |
| Bromide SCHEMBL3960568 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL3939821 | 0.88 | — | — | |
| SCHEMBL31026681 | 0.81 | FDPS (0.61) | FDPSCOPS5PSMD14SLC6A3STAMBP | |
| SCHEMBL735969 | 0.78 | — | — | |
| SCHEMBL6547517 | 0.77 | FDPS (0.51) | FDPSCOPS5PSMD14SLC6A3STAMBP | |
| SCHEMBL2089915 | 0.76 | FDPS (0.42) | FDPSCOPS5SLC6A3ALDH1A1HSD17B10 | |
| SCHEMBL6142897 | 0.76 | FDPS (0.65) | FDPSSLC6A3ALDH1A1HSD17B10TSHR | |
| SCHEMBL10709303 | 0.75 | FDPS (0.50) | FDPS | |
| SCHEMBL9256794 | 0.74 | FDPS (0.41) | FDPSCOPS5SLC6A3ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1379549-A2 | SEQUENCE OF THE PHOTORHABDUS LUMINESCENS STRAIN TT01 GENOME AND USES | INSTITUT PASTEUR (FR) | 2004-01-14 | — | — | EP | disclosed |
| WO-2002094867-A2 | SEQUENCE OF THE PHOTORHABDUS LUMINESCENS STRAIN TT01 GENOME AND USES | INSTITUT PASTEUR (FR) | 2002-11-28 | — | — | WO | disclosed |
| CN-1317051-A | HMP-P rinase and TMP-PPase from arabidopsis thaliana and their use in herbicide screening | SINGENPE AG (CH) | 2001-10-10 | — | — | CN | disclosed |