Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM3 | Q14832 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6151062 | 0.91 | OPRK1 (0.42) | GRM3SMN1; SMN2SIGMAR1MIFHRH3 | |
| SCHEMBL2390775 | 0.78 | MEN1 (0.68) | RAB9AMEN1ALDH1A1CYP2D6KMT2A | |
| SCHEMBL6142920 | 0.74 | ALDH1A1 (0.45) | GRM3RAB9AMEN1ALDH1A1CYP2D6 | |
| SCHEMBL22488321 | 0.72 | ALDH1A1 (0.57) | RAB9AMEN1ALDH1A1CYP2D6KMT2A | |
| SCHEMBL22488317 | 0.72 | ALDH1A1 (0.57) | RAB9AMEN1ALDH1A1CYP2D6KMT2A | |
| SCHEMBL13650590 | 0.72 | ALDH1A1 (0.57) | RAB9AMEN1ALDH1A1CYP2D6KMT2A | |
| SCHEMBL3391134 | 0.71 | SLC18A3 (0.60) | GRM3RAB9AMEN1ALDH1A1KMT2A | |
| SCHEMBL22023702 | 0.70 | HRH3 (0.52) | MEN1KMT2ASMN1; SMN2HRH3 | |
| SCHEMBL6795794 | 0.70 | SIGMAR1 (0.64) | SIGMAR1HRH3 | |
| SCHEMBL6800161 | 0.70 | SIGMAR1 (0.64) | SIGMAR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021186-B1 | PURINE INHIBITORS OF CYCLIN DEPENDENT KINASE 2 AND IkappaB-alpha | CV THERAPEUTICS INC (US) | 2005-06-29 | — | — | EP | disclosed |