Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NAAA | Q02083 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6154648 | 0.86 | CYP4F2 (0.42) | ACP1KMT2AHPGDCYP4F2CYP4A11 | |
| SCHEMBL6142857 | 0.85 | CYP4F2 (0.40) | KMT2ANAAAHPGDCYP4F2CYP4A11 | |
| SCHEMBL6142980 | 0.85 | F10 (0.43) | ACP1KMT2A | |
| SCHEMBL6143437 | 0.85 | ACP1 (0.40) | ACP1KMT2AMEN1P2RY12 | |
| SCHEMBL6143785 | 0.81 | GPR119 (0.39) | KMT2AHPGDCYP4F2CYP4A11MAP2K1 | |
| SCHEMBL6143729 | 0.79 | KMT2A (0.36) | ACP1KMT2ANAAACYP4F2CYP4A11 | |
| SCHEMBL6143541 | 0.78 | P2RY12 (0.36) | KMT2ACYP4F2CYP4A11P2RY12 | |
| SCHEMBL5567468 | 0.77 | ACP1 (0.53) | ACP1HPGDMAPTKDM4ELMNA | |
| SCHEMBL5563059 | 0.77 | ACP1 (0.53) | ACP1HPGDMAPTKDM4ELMNA | |
| SCHEMBL5562593 | 0.76 | ACP1 (0.52) | ACP1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1585731-A2 | HISTAMINE H3 RECEPTOR ANTAGONISTS, PREPARATON AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2005-10-19 | — | — | EP | disclosed |
| WO-2004026837-A2 | HISTAMINE H3 RECEPTOR ANTAGONISTS, PREPARATON AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2004-04-01 | — | — | WO | disclosed |