SCHEMBL614579

SCHEMBL614579

CC(C)(C)O[Si](Cl)(Cl)OC(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5029951 0.87 ALDH1A1 (0.33) ALDH1A1
SCHEMBL1804238 0.80
SCHEMBL525906 0.80 TSHR (0.31) ALDH1A1TSHRTDP1
SCHEMBL5029875 0.80
SCHEMBL5034161 0.80
SCHEMBL2818709 0.77
SCHEMBL10894108 0.77
SCHEMBL15526618 0.74
SCHEMBL5548519 0.72 ALDH1A1 (0.33) ALDH1A1
SCHEMBL6902480 0.72 TDP1 (0.31) ALDH1A1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0447066-B2 Pneumatic tyres BRIDGESTONE CORP (JP) 2000-08-16 EP claimed
US-5409969-A Comprising silica filler, carbon black, silane coupler, living polymer of butadiene-styrene BRIDGESTONE CORPORATION (JP) 1995-04-25 US claimed
EP-0447066-A1 Pneumatic tyres Bridgestone Corporation (JP) 1991-09-18 EP claimed
US-5017636-A Also containing polyisoprene, natural rubber, butadiene-styrene copolymer, wear and heat resistance, resilience JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1991-05-21 US claimed
EP-4232502-B1 POLYMERIC ALKYL SILICATES WACKER CHEMIE AG (DE) 2024-03-27 EP disclosed
WO-2019176592-A1 METHOD FOR PRODUCING HETEROATOM-CONTAINING AROMATIC VINYL COMPOUND 住友ゴム工業株式会社 2019-09-19 WO disclosed
US-9790359-B2 Tread rubber composition and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2017-10-17 US disclosed
US-9375484-B2 Taxane silicate prodrugs and nanoparticles REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2016-06-28 US disclosed
US-20150099823-A1 TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2015-04-09 US disclosed
EP-2857446-A1 TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE Sumitomo Rubber Industries, Ltd. (JP) 2015-04-08 EP disclosed
EP-1721930-B1 RUBBER COMPOSITION JSR CORP (JP) 2015-01-28 EP disclosed
US-20140213550-A1 SILICATE PRODRUGS AND NANOPARTICLES REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2014-07-31 US disclosed
WO-1994006811-A1 SILOXY OLIGONUCLEOTIDE ANALOGS INTEGRATED DNA TECHNOLOGIES, INC. (US) 1994-03-31 WO disclosed
US-5208359-A Process for the preparation of di-tert.butoxydiacetoxysilane HUELS AKTIENGESELLSCHAFT (DE) 1993-05-04 US disclosed
EP-0299074-B1 TIRE Bridgestone Corporation (JP) 1992-01-29 EP disclosed
US-5066721-A TIRES MADE OF SILICA FILLED, SILANE MODIFIED RUBBER BRIDGESTONE CORPORATION (JP) 1991-11-19 US disclosed
EP-0447066-A1 Pneumatic tyres Bridgestone Corporation (JP) 1991-09-18 EP disclosed
US-5017636-A Also containing polyisoprene, natural rubber, butadiene-styrene copolymer, wear and heat resistance, resilience JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1991-05-21 US disclosed
EP-0299074-A1 TIRE Bridgestone Corporation (JP) 1989-01-18 EP disclosed
US-4363902-A Process and heavy metal catalyst for the polymerization of α-olefins, particularly polyethylene WACKER-CHEMIE GMBH (DE) 1982-12-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140213550-A1 SILICATE PRODRUGS AND NANOPARTICLES CASP3, S1PR3, SLCO1B3 ALDH1A1 1474/4885TSHR 3141/4885TDP1 1390/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.