SCHEMBL6902480

SCHEMBL6902480

CC(C)(C)O[Si]([O])(OC(C)(C)C)OC(C)(C)C

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.31
TSHR P16473 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL614579 0.72 ALDH1A1 (0.33) TDP1TSHRALDH1A1
SCHEMBL705895 0.69 TDP1 (0.31) TDP1TSHRALDH1A1
SCHEMBL1803047 0.69 TDP1 (0.31) TDP1TSHRALDH1A1
SCHEMBL180305 0.67 ALDH1A1 (0.36) TDP1TSHRALDH1A1
SCHEMBL180050 0.65
SCHEMBL23706467 0.64 ALDH1A1 (0.33) TDP1TSHRALDH1A1
SCHEMBL190678 0.64 ALDH1A1 (0.33) TDP1TSHRALDH1A1
Fluoride SCHEMBL16568734 0.64 ALDH1A1 (0.33) TDP1TSHRALDH1A1
SCHEMBL426245 0.64 ALDH1A1 (0.33) TDP1TSHRALDH1A1
SCHEMBL703161 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3019511-B1 IMMOBILIZED METATHESIS TUNGSTEN CATALYSTS AND USE THEREOF IN OLEFIN METATHESIS XIMO AG (CH) 2019-01-02 EP disclosed
US-20160168283-A1 CHROMIUM(III) SILICATE CATALYSTS SUITABLE FOR PE SYNTHESIS ETH ZURICH (CH) 2016-06-16 US disclosed
EP-3022232-A1 CHROMIUM(III) SILICATE CATALYSTS SUITABLE FOR PE SYNTHESIS ETH Zurich (CH) 2016-05-25 EP disclosed
EP-3019511-A1 IMMOBILIZED METATHESIS TUNGSTEN CATALYSTS AND USE THEREOF IN OLEFIN METATHESIS XiMo AG (CH) 2016-05-18 EP disclosed
US-20160122375-A1 IMMOBILIZED METATHESIS TUNGSTEN CATALYSTS AND USE THEREOF IN OLEFIN METATHESIS VERBIO VEREINIGTE BIOENERGIE AG (DE) 2016-05-05 US disclosed
WO-2015007828-A1 CHROMIUM(III) SILICATE CATALYSTS SUITABLE FOR PE SYNTHESIS ETH ZURICH (CH) 2015-01-22 WO disclosed
EP-2826795-A1 Chromium(III) silicate catalysts suitable for PE synthesis ETH Zurich (CH) 2015-01-21 EP disclosed
WO-2015003815-A1 IMMOBILIZED METATHESIS TUNGSTEN CATALYSTS AND USE THEREOF IN OLEFIN METATHESIS XIMO AG (CH) 2015-01-15 WO disclosed
US-20040242782-A1 Rubber composition and vulcanized rubber SUMITOMO CHEMICAL COMPANY, LIMITED 2004-12-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160122375-A1 IMMOBILIZED METATHESIS TUNGSTEN CATALYSTS AND USE THEREOF IN OLEFIN METATHESIS NR1H3, NR1H2, RCOR3 TDP1 3829/4885TSHR 71/4885ALDH1A1 3029/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.