Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 6/20 | 0.53 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.53 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.53 |
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | HTR5A | P47898 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL614041 | 0.82 | KIT (0.58) | KITNQO2HTR2CHTR2BHTR5A | |
| SCHEMBL2311050 | 0.80 | KIT (0.49) | KITPDGFRAFGFR3NQO2ACHE | |
| SCHEMBL10022320 | 0.78 | KIT (0.46) | KITPDGFRAFGFR3NQO2BCHE | |
| SCHEMBL12387156 | 0.78 | KIT (0.47) | KITPDGFRAFGFR3NQO2HTR2C | |
| SCHEMBL614042 | 0.78 | MAOA (0.55) | KITNQO2BCHEDYRK1AKDM4E | |
| SCHEMBL11096433 | 0.77 | MAOA (0.55) | KITNQO2HTR2CBCHEACHE | |
| SCHEMBL6456554 | 0.76 | MAOA (0.61) | KITPDGFRAFGFR3HTR2CHTR2B | |
| SCHEMBL24276808 | 0.75 | KIT (0.64) | KITPDGFRAFGFR3HTR2CHTR2B | |
| SCHEMBL5361349 | 0.75 | KIT (0.51) | KITPDGFRAFGFR3NQO2HTR2C | |
| Dimethylamine SCHEMBL8548190 | 0.74 | KIT (0.46) | KITPDGFRAFGFR3NQO2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8604048-B2 | Pyridocarbazole type compounds and applications thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2013-12-10 | — | — | US | disclosed |
| US-20120041017-A1 | PYRIDOCARBAZOLE TYPE COMPOUNDS AND APPLICATIONS THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-02-16 | — | — | US | disclosed |
| US-20120041017-A1 | PYRIDOCARBAZOLE TYPE COMPOUNDS AND APPLICATIONS THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-02-16 | — | — | US | disclosed |
| US-20120041017-A1 | PYRIDOCARBAZOLE TYPE COMPOUNDS AND APPLICATIONS THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-02-16 | — | — | US | disclosed |
| WO-2010095042-A2 | PYRIDOCARBAZOLE TYPE COMPOUNDS AND APPLICATIONS THEREOF | CENTRE NATONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2010-08-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120041017-A1 | PYRIDOCARBAZOLE TYPE COMPOUNDS AND APPLICATIONS THEREOF | NLN, OPA1, PYCR1 | KIT 4688/4885PDGFRA 3344/4885FGFR3 3741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.