Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.59 |
| ▸ | DGKA | P23743 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PAM | P19021 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15299916 | 1.00 | NAAA (0.59) | NAAADGKAGAAPRKCALMNA | |
| SCHEMBL3794062 | 1.00 | NAAA (0.59) | NAAADGKAGAAPRKCALMNA | |
| SCHEMBL2340491 | 1.00 | NAAA (0.59) | NAAADGKAGAAPRKCALMNA | |
| SCHEMBL17734434 | 1.00 | NAAA (0.59) | NAAADGKAGAAPRKCALMNA | |
| SCHEMBL3787448 | 1.00 | NAAA (0.59) | NAAADGKAGAAPRKCALMNA | |
| SCHEMBL226443 | 1.00 | NAAA (0.59) | NAAADGKAGAAPRKCALMNA | |
| SCHEMBL9747148 | 1.00 | NAAA (0.59) | NAAADGKAGAAPRKCALMNA | |
| SCHEMBL3782110 | 1.00 | NAAA (0.59) | NAAADGKAGAAPRKCALMNA | |
| SCHEMBL18473229 | 1.00 | NAAA (0.59) | NAAADGKAGAAPRKCALMNA | |
| SCHEMBL14525067 | 1.00 | NAAA (0.59) | NAAADGKAGAAPRKCALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250221968-A1 | TREATMENTS AND METHODS FOR INCREASING DOPAMINE | UNIV OXFORD INNOVATION LTD (GB) | 2025-07-10 | — | — | US | claimed |
| EP-4493171-A1 | NICOTINIC ACETYLCHOLINE RECEPTOR ANTAGONIST/BLOCKER FOR USE IN INCREASING DOPAMINE | Zhang, Yanfeng C/o Oxford University Innovation Limited (GB) | 2025-01-22 | — | — | EP | claimed |
| WO-2023175357-A1 | NICOTINIC ACETYLCHOLINE RECEPTOR ANTAGONIST/BLOCKER FOR USE IN INCREASING DOPAMINE | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2023-09-21 | — | — | WO | claimed |
| US-8980923-B2 | Compositions and methods for selective inhibition of nicotine acetylcholine receptors | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-03-17 | — | — | US | claimed |
| US-20120329783-A1 | COMPOSITIONS AND METHODS FOR SELECTIVE INHIBITION OF NICOTINE ACETYLCHOLINE RECEPTORS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-12-27 | — | — | US | claimed |
| US-7531555-B2 | Compositions and methods for selective inhibition of nicotine acetylcholine receptors | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2009-05-12 | — | — | US | claimed |
| US-20090062339-A1 | COMPOSITIONS AND METHODS FOR SELECTIVE INHIBITION OF NICOTINE ACETYLCHOLINE RECEPTORS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-03-05 | — | — | US | claimed |
| US-20050119309-A1 | Compositions and methods for selective inhibition of nicotine acetylcholine receptors | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-06-02 | — | — | US | claimed |
| WO-2005032479-A2 | COMPOSITIONS AND METHODS FOR SELECTIVE INHIBITION OF NICOTINE ACETYLCHOLINE RECEPTORS | UNVIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2005-04-14 | — | — | WO | claimed |
| US-20250221968-A1 | TREATMENTS AND METHODS FOR INCREASING DOPAMINE | UNIV OXFORD INNOVATION LTD (GB) | 2025-07-10 | — | — | US | disclosed |
| EP-4493171-A1 | NICOTINIC ACETYLCHOLINE RECEPTOR ANTAGONIST/BLOCKER FOR USE IN INCREASING DOPAMINE | Zhang, Yanfeng C/o Oxford University Innovation Limited (GB) | 2025-01-22 | — | — | EP | disclosed |
| WO-2023175357-A1 | NICOTINIC ACETYLCHOLINE RECEPTOR ANTAGONIST/BLOCKER FOR USE IN INCREASING DOPAMINE | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2023-09-21 | — | — | WO | disclosed |
| US-20220033490-A1 | METHODS AND COMPOSITIONS FOR TREATING CANCER USING CHRNA6 INHIBITORS | FLAGSHIP PIONEERING INNOVATIONS V INC (US) | 2022-02-03 | — | — | US | disclosed |
| US-8980923-B2 | Compositions and methods for selective inhibition of nicotine acetylcholine receptors | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-03-17 | — | — | US | disclosed |
| US-20090062339-A1 | COMPOSITIONS AND METHODS FOR SELECTIVE INHIBITION OF NICOTINE ACETYLCHOLINE RECEPTORS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-03-05 | — | — | US | disclosed |
| WO-2005032479-A3 | COMPOSITIONS AND METHODS FOR SELECTIVE INHIBITION OF NICOTINE ACETYLCHOLINE RECEPTORS | UNVIVERSITY OF FLORIDA RES FOU (US) | 2005-09-15 | — | — | WO | disclosed |
| US-20050119309-A1 | Compositions and methods for selective inhibition of nicotine acetylcholine receptors | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-06-02 | — | — | US | disclosed |
| US-20050119309-A1 | Compositions and methods for selective inhibition of nicotine acetylcholine receptors | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-06-02 | — | — | US | disclosed |
| WO-2005032479-A2 | COMPOSITIONS AND METHODS FOR SELECTIVE INHIBITION OF NICOTINE ACETYLCHOLINE RECEPTORS | UNVIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2005-04-14 | — | — | WO | disclosed |
| WO-2005032479-A2 | COMPOSITIONS AND METHODS FOR SELECTIVE INHIBITION OF NICOTINE ACETYLCHOLINE RECEPTORS | UNVIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2005-04-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062339-A1 | COMPOSITIONS AND METHODS FOR SELECTIVE INHIBITION OF NICOTINE ACETYLCHOLINE RECEPTORS | CHRNA5, CHRNA6, CHRNA3 | NAAA 653/4885DGKA 3465/4885GAA 3290/4885 |
| US-20050119309-A1 | Compositions and methods for selective inhibition of nicotine acetylcholine receptors | CHRNA5, CHRNA6, CHRNA3 | NAAA 653/4885DGKA 3465/4885GAA 3290/4885 |
| US-20120329783-A1 | COMPOSITIONS AND METHODS FOR SELECTIVE INHIBITION OF NICOTINE ACETYLCHOLINE RECEPTORS | CHRNA5, CHRNA6, CHRNA3 | NAAA 653/4885DGKA 3465/4885GAA 3290/4885 |
| US-20220033490-A1 | METHODS AND COMPOSITIONS FOR TREATING CANCER USING CHRNA6 INHIBITORS | CHRNA6, CHRNA1, CHRNB1 | NAAA 576/4885DGKA 2074/4885GAA 2411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.