SCHEMBL614872

SCHEMBL614872

NCCNC(=O)OCc1ccccc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.71
SMN1; SMN2 Q16637 1/20 0.71
HTT P42858 1/20 0.67
TGM2 P21980 1/20 0.58
SLC1A3 P43003 1/20 0.58
SLC1A1 P43005 1/20 0.58
L3MBTL1 Q9Y468 2/20 0.57
KEAP1 Q14145 2/20 0.57
NFE2L2 Q16236 2/20 0.57
MAPT P10636 1/20 0.56
CA12 O43570 2/20 0.55
CA1 P00915 2/20 0.55
CA2 P00918 2/20 0.55
CA9 Q16790 2/20 0.55
PLAU P00749 1/20 0.54
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
SPHK2 Q9NRA0 1/20 0.51
KAT2B Q92831 1/20 0.51
GAA P10253 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL334749 0.98 LMNA (0.69) LMNASMN1; SMN2HTTTGM2SLC1A3
(Chloromethyl)Benzene SCHEMBL28649859 0.92 HTT (0.62) LMNASMN1; SMN2HTTTGM2SLC1A3
SCHEMBL14486856 0.91 HTT (0.64) LMNASMN1; SMN2HTTTGM2SLC1A3
SCHEMBL15671941 0.91 HTT (0.64) LMNASMN1; SMN2HTTTGM2SLC1A3
SCHEMBL615296 0.90 HTT (0.72) LMNASMN1; SMN2HTTTGM2SLC1A3
SCHEMBL25132908 0.89 PRSS1 (0.59) LMNASMN1; SMN2HTTTGM2SLC1A3
SCHEMBL13055383 0.89 LMNA (0.80) LMNASMN1; SMN2HTTTGM2SLC1A3
Hydrochloric Acid SCHEMBL616935 0.89 HTT (0.70) LMNASMN1; SMN2HTTTGM2SLC1A3
SCHEMBL335088 0.89 HTT (0.70) LMNASMN1; SMN2HTTTGM2SLC1A3
SCHEMBL4363476 0.87 HTT (0.68) LMNASMN1; SMN2HTTTGM2SLC1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 691 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025118255-A1 RADIOLABELED FAPI COMPLEX, PREPARATION METHOD THEREFOR, AND USE THEREOF 北京师范大学 2025-06-12 WO claimed
CN-119604492-A Radiolabeled FAPI complex and preparation method and application thereof 北京师范大学 2025-03-11 CN claimed
CN-116023643-A Acid-sensitive polymer containing beta-carboxyl amide bond, and preparation method and application thereof 复旦大学 2023-04-28 CN claimed
CN-114377142-A ROS-responsive prodrug realizing deep delivery by pH response and step-by-step targeting 宁波大学 2022-04-22 CN claimed
CN-104557704-B Preparation method of pixantrone maleate 北京凯莱天成医药科技有限公司 2017-05-10 CN claimed
US-5602161-A ELASTASE INHIBITORS; PREVENTING AND TREATING EMPHYSEMA, ENDOTOXIN-INDUCED LUNG DISORDERS WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) 1997-02-11 US claimed
EP-0676396-A1 Tetrazolylphenyl pivalate derivatives and medicinal composition containing the same as effective component Wakamoto Pharmaceutical Co., Ltd. (JP) 1995-10-11 EP claimed
EP-4745237-A1 RNAI AGENT FOR INHIBITING EXPRESSION OF KETOHEXOKINASE AND USE THEREOF YUN HO BIO CO., LTD (CN) 2026-05-20 EP disclosed
EP-4739345-A1 BORONATED HYDROGELS AND METHODS OF MAKING AND USING THE SAME Boston Scientific Scimed, Inc. (US) 2026-05-13 EP disclosed
EP-4725560-A2 ANTI-B7H3 ANTIBODIES FOR THE PREPARATION OF ANTIBODY DRUG CONJUGATES (ADCS) OF KSP INHIBITORS Bayer Pharma Aktiengesellschaft (DE) 2026-04-15 EP disclosed
US-20260091081-A1 A FORMULATION OF A CONJUGATE OF A TUBULYSIN ANALOG TO A CELL-BINDING MOLECULE HANGZHOU DAC BIOTECH CO., LTD (CN) 2026-04-02 US disclosed
US-12576124-B2 Formulation of a conjugate of a tubulysin analog to a cell-binding molecule HANGZHOU DAC BIOTECH CO., LTD (CN) 2026-03-17 US disclosed
US-20260061065-A1 ANTIBODY DRUG CONJUGATES NOVARTIS AG (CH) 2026-03-05 US disclosed
WO-1983003828-A1 1-CARBOXYALKANOYLPERHYDROINDOLE-2-CARBOXYLIC ACIDS AND DERIVATIVES CIBA-GEIGY AG (CH) 1983-11-10 WO disclosed
EP-0013147-B1 POLYMERISABLE MONOMERS, THEIR USE TO PREPARE CROSS-LINKABLE POLYMERS AND THE CROSS-LINKABLE POLYMERS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1983-10-26 EP disclosed
US-4346231-A Polymerizable ethylenically unsaturated amide compounds PONTICELLO IGNAZIO S 1982-08-24 US disclosed
US-4247673-A COLOR COUPLERS, PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1981-01-27 US disclosed
US-4215195-A CROSSLINKABLE, POLYMERIC COLOR COUPLERS, GELATIN EXTENDERS, BINDERS EASTMAN KODAK COMPANY (US) 1980-07-29 US disclosed
EP-0013147-A2 POLYMERISABLE MONOMERS, THEIR USE TO PREPARE CROSS-LINKABLE POLYMERS AND THE CROSS-LINKABLE POLYMERS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1980-07-09 EP disclosed
US-4178371-A ANALGESIC, NARCOTIC ANTAGONIST OR ANTIDIARRHEAL AGENT RECKITT & COLMAN PRODUCTS LIMITED (GB) 1979-12-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12576124-B2 Formulation of a conjugate of a tubulysin analog to a cell-binding molecule CD4, TAP1, MCTS1 LMNA 2109/4885SMN1; SMN2 1758/4885HTT 1768/4885
US-20260061065-A1 ANTIBODY DRUG CONJUGATES FCGR2A, FCGR3B, BCL3 LMNA 254/4885SMN1; SMN2 1063/4885HTT 2649/4885
US-20260091081-A1 A FORMULATION OF A CONJUGATE OF A TUBULYSIN ANALOG TO A CELL-BINDING MOLECULE CD4, MALT1, LY6K LMNA 2507/4885SMN1; SMN2 3725/4885HTT 2917/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.