Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TOP1 | P11387 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30628889 | 1.00 | MAOB (0.59) | MAOBALOX5LMNACYP1A2PTGS1 | |
| SCHEMBL7390468 | 0.88 | MAOB (0.58) | MAOBGAAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL6119729 | 0.88 | MAOB (0.58) | MAOBALOX5LMNAMAOAGAA | |
| SCHEMBL31525501 | 0.88 | MAOB (0.58) | MAOBGAAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL31725937 | 0.88 | MAOB (0.58) | MAOBALOX5LMNAMAOAGAA | |
| SCHEMBL17386359 | 0.88 | MAOB (0.50) | MAOBALOX5LMNACYP1A2PTGS1 | |
| SCHEMBL320716 | 0.87 | MAPK1 (0.54) | MAOBALOX5LMNARAB9ACYP3A4 | |
| SCHEMBL7400820 | 0.87 | MAOB (0.57) | MAOBGAAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL7778474 | 0.86 | MAOB (0.59) | MAOBALOX5LMNACYP1A2PTGS1 | |
| SCHEMBL3823883 | 0.85 | MAOB (0.62) | MAOBALOX5LMNACYP1A2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1121125-A1 | PHARMACEUTICAL FORMULATIONS FOR USE IN ESTROGEN DEPRIVATION SYNDROME | ELI LILLY AND COMPANY (US) | 2001-08-08 | — | — | EP | claimed |
| WO-2000021535-A1 | PHARMACEUTICAL FORMULATIONS FOR USE IN ESTROGEN DEPRIVATION SYNDROME | ELI LILLY AND COMPANY (US) | 2000-04-20 | — | — | WO | claimed |
| EP-4698520-A1 | RAF-MEK PROTEIN COMPLEX MODULATORS AND METHODS OF USE THEREOF | Gandeeva Therapeutics, Inc. (US) | 2026-02-25 | — | — | EP | disclosed |
| US-20250288553-A1 | Antimicrobial Compositions and Uses for Treatment of Clostridioides difficile, Mycobacterium tuberculosis, and Enterococcus faecalis Infection | THE UNIVERSITY OF TOLEDO | 2025-09-18 | — | — | US | disclosed |
| WO-2024220708-A1 | RAF-MEK PROTEIN COMPLEX MODULATORS AND METHODS OF USE THEREOF | GANDEEVA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |
| WO-2023244764-A1 | COMPOUNDS FOR THE TARGETED DEGRADATION OF SMARCA2 | C4 THERAPEUTICS, INC. (US) | 2023-12-21 | — | — | WO | disclosed |
| WO-2023239750-A1 | BICYCLIC-SUBSTITUTED GLUTARIMIDE CEREBLON BINDERS | C4 THERAPEUTICS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |
| US-20230399282-A1 | Series of Skin-Whitening (Lightening) Compounds | UNIGEN, INC. (US) | 2023-12-14 | — | — | US | disclosed |
| WO-2023215619-A2 | ANTIMICROBIAL COMPOSITIONS AND USES FOR TREATMENT OF CLOSTRIDIOIDES DIFFICILE, MYCOBACTERIUM TUBERCULOSIS, AND ENTEROCOCCUS FAECALIS INFECTION | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2023-11-09 | — | — | WO | disclosed |
| US-11739040-B2 | Series of skin-whitening (lightening) compounds | UNIGEN, INC. (US) | 2023-08-29 | — | — | US | disclosed |
| EP-3542780-B1 | SERIES OF SKIN-WHITENING (LIGHTENING) COMPOUNDS | UNIGEN INC (US) | 2022-01-19 | — | — | EP | disclosed |
| US-4387229-A | ANALGESICS, TRANQUILIZERS, SEDATIVES | PFIZER INC. (US) | 1983-06-07 | — | — | US | disclosed |
| US-4371720-A | ANTIDIARRHEALS, ANTIEMETICS | PFIZER INC. (US) | 1983-02-01 | — | — | US | disclosed |
| US-4332942-A | 3-(2-Hydroxy-4-(substituted)phenyl)azacycloalkanes as analgesics | PFIZER, INC. (US) | 1982-06-01 | — | — | US | disclosed |
| EP-0048572-A2 | Substituted 2-hydroxyphenyl cycloalkanes and pharmaceutical compositions thereof | PFIZER INC. (US) | 1982-03-31 | — | — | EP | disclosed |
| US-4306097-A | 3-[2-Hydroxy-4-(substituted)phenyl]-cycloalkanol analgesic agents | PFIZER INC. (US) | 1981-12-15 | — | — | US | disclosed |
| US-4284829-A | Hydroxyalkyl and oxoalkyl substituted phenols as analgesics and sedatives | PFIZER INC. (US) | 1981-08-18 | — | — | US | disclosed |
| US-4283569-A | Hydroxyalkyl and oxoalkyl substituted phenols as analgesics and sedatives | PFIZER INC. (US) | 1981-08-11 | — | — | US | disclosed |
| US-4263438-A | 3-[2,4-(Disubstituted)-phenyl]azacycloalkanones as analgesics | PFIZER INC. (US) | 1981-04-21 | — | — | US | disclosed |
| US-4147872-A | 3-[2-Hydroxy-4-(substituted)-phenyl]azacycloalkanes and derivatives thereof as analgesic agents and intermediates therefor | PFIZER INC. (US) | 1979-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11739040-B2 | Series of skin-whitening (lightening) compounds | TYR, TH, MAOB | MAOB 3/4885ALOX5 301/4885LMNA 3351/4885 |
| US-20250288553-A1 | Antimicrobial Compositions and Uses for Treatment of Clostridioides difficile, Mycobacterium tuberculosis, and Enterococcus faecalis Infection | VDR, CYP2R1, PTH1R | MAOB 2348/4885ALOX5 1908/4885LMNA 1748/4885 |
| US-20230399282-A1 | Series of Skin-Whitening (Lightening) Compounds | TYR, TH, MAOB | MAOB 3/4885ALOX5 301/4885LMNA 3351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.