Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6150725 | 0.84 | ALDH1A1 (0.49) | HPGDALDH1A1KMT2A | |
| SCHEMBL6149147 | 0.82 | PPARG (0.42) | MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL5354670 | 0.80 | PPARA (0.53) | EPHX2 | |
| SCHEMBL6148908 | 0.80 | AOC3 (0.49) | HPGDALDH1A1 | |
| SCHEMBL6150404 | 0.80 | PPARA (0.50) | — | |
| SCHEMBL6149805 | 0.79 | HPGD (0.51) | HPGD | |
| SCHEMBL6656765 | 0.75 | PPARA (0.46) | KMT2A | |
| SCHEMBL5353330 | 0.75 | TSHR (0.54) | HPGDALDH1A1KMT2A | |
| SCHEMBL5361731 | 0.75 | TSHR (0.54) | HPGDALDH1A1KMT2A | |
| SCHEMBL3963793 | 0.75 | TSHR (0.54) | HPGDALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1517882-A1 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-03-30 | — | — | EP | disclosed |
| WO-2004000789-A9 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | LILLY CO ELI (US) | 2004-03-11 | — | — | WO | disclosed |
| WO-2004000789-A1 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2003-12-31 | — | — | WO | disclosed |