Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.46 |
| ▸ | PPARG | P37231 | 6/20 | 0.45 |
| ▸ | TACR1 | P25103 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6150739 | 0.85 | PPARA (0.53) | PPARAPPARGTACR1KDM4EMEN1 | |
| SCHEMBL5358829 | 0.84 | PPARA (0.47) | PPARAPPARGKDM4EMEN1KMT2A | |
| SCHEMBL6150158 | 0.82 | PPARA (0.49) | PPARAPPARGTACR1PPARD | |
| SCHEMBL6148908 | 0.81 | AOC3 (0.49) | PPARAPPARGTACR1PPARD | |
| SCHEMBL6658216 | 0.78 | PPARA (0.51) | PPARAPPARGTACR1KDM4EMEN1 | |
| SCHEMBL6150826 | 0.75 | EPHX2 (0.44) | KMT2A | |
| SCHEMBL6150725 | 0.73 | ALDH1A1 (0.49) | PPARAPPARGMEN1KMT2A | |
| SCHEMBL6149147 | 0.73 | PPARG (0.42) | PPARAPPARGPPARD | |
| SCHEMBL6149560 | 0.72 | CTSD (0.41) | PPARAPPARGMEN1KMT2APPARD | |
| SCHEMBL6149805 | 0.71 | HPGD (0.51) | PPARAPPARGLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004000789-A9 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | LILLY CO ELI (US) | 2004-03-11 | — | — | WO | claimed |
| WO-2004000789-A9 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | LILLY CO ELI (US) | 2004-03-11 | — | — | WO | disclosed |