Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.42 |
| ▸ | PPARA | Q07869 | 7/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6150725 | 0.89 | ALDH1A1 (0.49) | PPARGPPARACA1CA2CNR1 | |
| SCHEMBL6149805 | 0.87 | HPGD (0.51) | PPARGPPARACNR1HTT | |
| SCHEMBL6150826 | 0.82 | EPHX2 (0.44) | ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL6150806 | 0.82 | PPARA (0.46) | PPARGPPARAPPARD | |
| SCHEMBL5364083 | 0.81 | TACR2 (0.40) | PPARGPPARACA1CA2CNR1 | |
| SCHEMBL6148908 | 0.78 | AOC3 (0.49) | PPARGPPARAPPARDALDH1A1HTT | |
| SCHEMBL6150597 | 0.77 | PPARA (0.47) | PPARGPPARAHTT | |
| SCHEMBL6658216 | 0.76 | PPARA (0.51) | PPARGPPARACNR1PPARD | |
| SCHEMBL6150313 | 0.74 | KMT2A (0.49) | PPARGPPARAPPARD | |
| SCHEMBL6656765 | 0.73 | PPARA (0.46) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1517882-A1 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-03-30 | — | — | EP | disclosed |
| WO-2004000789-A1 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2003-12-31 | — | — | WO | disclosed |