Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27625963 | 0.83 | SLC6A9 (0.44) | MEN1KMT2AALDH1A1SLC6A9CHRM2 | |
| SCHEMBL27625962 | 0.83 | SLC6A9 (0.44) | MEN1KMT2AALDH1A1SLC6A9CHRM2 | |
| SCHEMBL6151344 | 0.83 | MEN1 (0.44) | MEN1KMT2AALDH1A1SLC6A9CHRM2 | |
| SCHEMBL6150897 | 0.83 | MEN1 (0.44) | MEN1KMT2AALDH1A1SLC6A9CHRM2 | |
| SCHEMBL5375448 | 0.78 | OPRM1 (0.41) | MEN1KMT2ASLC6A9SLC6A5OPRM1 | |
| SCHEMBL5375451 | 0.78 | OPRM1 (0.41) | MEN1KMT2ASLC6A9SLC6A5OPRM1 | |
| SCHEMBL28758537 | 0.75 | SLC6A2 (0.46) | MEN1KMT2AALDH1A1SLC6A9CHRM2 | |
| SCHEMBL28758536 | 0.75 | SLC6A2 (0.46) | MEN1KMT2AALDH1A1SLC6A9CHRM2 | |
| SCHEMBL27626122 | 0.75 | CHRM2 (0.48) | MEN1KMT2ASLC6A9CHRM2CHRM3 | |
| SCHEMBL27626119 | 0.75 | CHRM2 (0.48) | MEN1KMT2ASLC6A9CHRM2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1594840-A1 | PIPERIDINE-BENZENESULFONAMIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2005-11-16 | — | — | EP | disclosed |
| WO-2004072034-A1 | PIPERIDINE-BENZENESULFONAMIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2004-08-26 | — | — | WO | disclosed |