Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 4/20 | 0.40 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6150897 | 1.00 | MEN1 (0.44) | MEN1KMT2AUTS2RCNR2HSD11B1 | |
| SCHEMBL6150894 | 0.83 | MEN1 (0.52) | MEN1KMT2AALDH1A1SLC6A9SLC6A5 | |
| SCHEMBL27625963 | 0.76 | SLC6A9 (0.44) | MEN1KMT2AHSD11B1ALDH1A1SLC6A9 | |
| SCHEMBL27625962 | 0.76 | SLC6A9 (0.44) | MEN1KMT2AHSD11B1ALDH1A1SLC6A9 | |
| SCHEMBL5765526 | 0.75 | MCHR1 (0.45) | MEN1KMT2AUTS2RCHRM2CHRM3 | |
| SCHEMBL5765522 | 0.75 | MCHR1 (0.45) | MEN1KMT2AUTS2RCHRM2CHRM3 | |
| SCHEMBL5375448 | 0.74 | OPRM1 (0.41) | MEN1KMT2ASLC6A9SLC6A5SLC18A3 | |
| SCHEMBL5375451 | 0.74 | OPRM1 (0.41) | MEN1KMT2ASLC6A9SLC6A5SLC18A3 | |
| SCHEMBL28758536 | 0.72 | SLC6A2 (0.46) | MEN1KMT2AALDH1A1SLC6A9SLC6A5 | |
| SCHEMBL28758537 | 0.72 | SLC6A2 (0.46) | MEN1KMT2AALDH1A1SLC6A9SLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1594840-A1 | PIPERIDINE-BENZENESULFONAMIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2005-11-16 | — | — | EP | disclosed |
| WO-2004072034-A1 | PIPERIDINE-BENZENESULFONAMIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2004-08-26 | — | — | WO | disclosed |