Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.75 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.75 |
| ▸ | BLM | P54132 | 2/20 | 0.75 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.75 |
| ▸ | TSHR | P16473 | 2/20 | 0.75 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.75 |
| ▸ | LMNA | P02545 | 1/20 | 0.75 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.75 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.75 |
| ▸ | DRD1 | P21728 | 1/20 | 0.75 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.75 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.75 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.75 |
| ▸ | DRD3 | P35462 | 1/20 | 0.75 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.75 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.75 |
| ▸ | EYA2 | O00167 | 1/20 | 0.70 |
| ▸ | APP | P05067 | 1/20 | 0.70 |
| ▸ | ACE | P12821 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21539376 | 1.00 | TDP1 (0.75) | TDP1ALOX15BLMPMP22KDM4E | |
| SCHEMBL1102344 | 0.97 | TDP1 (0.70) | TDP1ALOX15BLMPMP22KDM4E | |
| SCHEMBL1698787 | 0.97 | TDP1 (0.74) | TDP1ALOX15BLMPMP22KDM4E | |
| SCHEMBL5521524 | 0.95 | TDP1 (0.75) | TDP1ALOX15BLMPMP22KDM4E | |
| SCHEMBL19962177 | 0.95 | TDP1 (0.75) | TDP1ALOX15BLMPMP22KDM4E | |
| SCHEMBL8988039 | 0.95 | TDP1 (0.68) | TDP1ALOX15BLMPMP22KDM4E | |
| SCHEMBL12358747 | 0.92 | TDP1 (0.74) | TDP1ALOX15BLMPMP22KDM4E | |
| Edetic Acid SCHEMBL5934006 | 0.92 | TDP1 (0.74) | TDP1ALOX15BLMPMP22KDM4E | |
| SCHEMBL22571480 | 0.92 | TDP1 (0.70) | TDP1ALOX15BLMPMP22KDM4E | |
| SCHEMBL18251067 | 0.92 | TDP1 (0.65) | TDP1ALOX15BLMPMP22KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220017495-A1 | CONJUGATES OF BIVALENT EVANS BLUE DYE DERIVATIVES AND METHODS OF USE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2022-01-20 | — | — | US | disclosed |
| US-10696631-B2 | Chemical conjugates of evans blue derivatives and their use as radiotherapy and imaging agents | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2020-06-30 | — | — | US | disclosed |
| US-10689415-B2 | Conjugates of RGD peptides and (bacterio)chlorophyll photosensitizers | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2020-06-23 | — | — | US | disclosed |
| US-20190084931-A1 | CHEMICAL CONJUGATES OF EVANS BLUE DERIVATIVES AND THEIR USE AS RADIOTHERAPY AND IMAGING AGENTS | US HEALTH | 2019-03-21 | — | — | US | disclosed |
| US-9957293-B2 | Conjugates of RGD peptides and porphyrin or (bacterio)chlorophyll photosynthesizers and their uses | YEDA RESEARCH AND DEVELOPMENT COMPANY LTD. (IL) | 2018-05-01 | — | — | US | disclosed |
| WO-2017196806-A1 | CHEMICAL CONJUGATES OF EVANS BLUE DERIVATIVES AND THEIR USE AS RADIOTHERAPY AND IMAGING AGENTS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2017-11-16 | — | — | WO | disclosed |
| WO-2017116994-A1 | UREA-BASED PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) INHIBITORS FOR IMAGING AND THERAPY | FIVE ELEVEN PHARMA INC. (US) | 2017-07-06 | — | — | WO | disclosed |
| US-20140065075-A1 | TARGETED CONTRAST AGENTS AND USES THEREOF | RF THERAPEUTICS INC. (CA) | 2014-03-06 | — | — | US | disclosed |
| US-20110229384-A1 | CONCENTRATE QUALITY IN THE ENRICHMENT OF UG-2 PLATINUM ORE | BASF SE (DE) | 2011-09-22 | — | — | US | disclosed |
| US-20100204508-A1 | DENDRITIC COMPOUND AND USE THEREOF | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2010-08-12 | — | — | US | disclosed |
| US-20090148384-A1 | FUNCTIONALIZED, SOLID POLYMER NANOPARTICLES COMPRISING EPOTHILONES | BAYER SCHERING PHARMA AG (DE) | 2009-06-11 | — | — | US | disclosed |
| US-20090148384-A1 | FUNCTIONALIZED, SOLID POLYMER NANOPARTICLES COMPRISING EPOTHILONES | BAYER SCHERING PHARMA AG (DE) | 2009-06-11 | — | — | US | disclosed |
| US-7445767-B2 | In-vivo diagnostic method by near infrared radiation | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH AN DER FREIEN UNIVERSITAT BERLIN (DE) | 2008-11-04 | — | — | US | disclosed |
| US-7445767-B2 | In-vivo diagnostic method by near infrared radiation | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH AN DER FREIEN UNIVERSITAT BERLIN (DE) | 2008-11-04 | — | — | US | disclosed |
| US-7288144-B2 | Non-aqueous ink-jet ink composition | RISO KAGAKU CORPORATION (JP) | 2007-10-30 | — | — | US | disclosed |
| EP-1509254-A1 | NEW AGENTS FOR MAGNETIC IMAGING METHOD | Bracco Imaging S.p.A. (IT) | 2005-03-02 | — | — | EP | disclosed |
| WO-2003103722-A1 | NEW AGENTS FOR MAGNETIC IMAGING METHOD | BRACCO IMAGING S.P.A. (IT) | 2003-12-18 | — | — | WO | disclosed |
| US-20020049190-A1 | Pharmaceutical compositions comprising metal complexes | ANORMED INC. (CA) | 2002-04-25 | — | — | US | disclosed |
| EP-1163247-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING METAL COMPLEXES | ANORMED INC. (CA) | 2001-12-19 | — | — | EP | disclosed |
| WO-2000056743-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING METAL COMPLEXES | ANORMED INC. (CA) | 2000-09-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190084931-A1 | CHEMICAL CONJUGATES OF EVANS BLUE DERIVATIVES AND THEIR USE AS RADIOTHERAPY AND IMAGING AGENTS | H1-4, VIP, H1-3 | TDP1 3854/4885ALOX15 3157/4885BLM 3495/4885 |
| US-10689415-B2 | Conjugates of RGD peptides and (bacterio)chlorophyll photosensitizers | MVD, AGER, FOLH1 | TDP1 1667/4885ALOX15 1323/4885BLM 1201/4885 |
| US-20090148384-A1 | FUNCTIONALIZED, SOLID POLYMER NANOPARTICLES COMPRISING EPOTHILONES | EPOR, SELPLG, SELP | TDP1 4818/4885ALOX15 1843/4885BLM 4880/4885 |
| US-20020049190-A1 | Pharmaceutical compositions comprising metal complexes | CFD, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, F12 | TDP1 3584/4885ALOX15 1531/4885BLM 2507/4885 |
| US-20140065075-A1 | TARGETED CONTRAST AGENTS AND USES THEREOF | ANTXR2, CALCOCO2, PAICS | TDP1 4496/4885ALOX15 1393/4885BLM 4381/4885 |
| US-20220017495-A1 | CONJUGATES OF BIVALENT EVANS BLUE DYE DERIVATIVES AND METHODS OF USE | NUCB2, RNPEP, MME | TDP1 3438/4885ALOX15 2483/4885BLM 4633/4885 |
| US-10696631-B2 | Chemical conjugates of evans blue derivatives and their use as radiotherapy and imaging agents | H1-4, VIP, H1-3 | TDP1 3854/4885ALOX15 3157/4885BLM 3495/4885 |
| US-20100204508-A1 | DENDRITIC COMPOUND AND USE THEREOF | CXCL10, PDCD1LG2, PDCD5 | TDP1 4722/4885ALOX15 2192/4885BLM 3817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.