Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | GHSR | Q92847 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12311331 | 0.81 | ALDH1A1 (0.52) | ALDH1A1IDO1CA1CA2MAPT | |
| SCHEMBL4818407 | 0.79 | APP (0.43) | HTTALDH1A1CA1CA2MAPT | |
| SCHEMBL6150769 | 0.78 | CA1 (0.45) | CA1CA2MAPTCA12CA9 | |
| Hydrochloric Acid SCHEMBL4824149 | 0.78 | GAA (0.42) | HTTALDH1A1CA1CA2MAPT | |
| SCHEMBL12201441 | 0.74 | LATS1 (0.49) | HPGDMAPTL3MBTL1 | |
| SCHEMBL4824452 | 0.72 | MAPT (0.63) | HPGDHTTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL17058229 | 0.72 | MAPT (0.45) | LMNAKDM4EALDH1A1IDO1MAPT | |
| SCHEMBL12311256 | 0.70 | ALDH1A1 (0.59) | LMNAHTTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL14253805 | 0.69 | ALDH1A1 (0.44) | LMNAHTTALDH1A1CA1CA2 | |
| Hydrochloric Acid SCHEMBL9734655 | 0.68 | HPGD (0.46) | LMNAHPGDHTTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1278723-B1 | P-(SULFONYL)-ARYL AND -HETEROARYL AMINES | HOFFMANN LA ROCHE (CH) | 2005-08-31 | — | — | EP | disclosed |