Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12311256 | 0.88 | ALDH1A1 (0.59) | ALDH1A1MAPTKEAP1CA2CA12 | |
| SCHEMBL4818407 | 0.82 | APP (0.43) | ALDH1A1MAPTKEAP1CA2CA12 | |
| SCHEMBL26422118 | 0.82 | ALDH1A1 (0.50) | ALDH1A1MAPTKEAP1CA2CA12 | |
| SCHEMBL6151111 | 0.81 | LMNA (0.39) | ALDH1A1MAPTCA2CA12CA9 | |
| SCHEMBL4411321 | 0.81 | ALDH1A1 (0.54) | ALDH1A1MAPTKEAP1CA2CA12 | |
| SCHEMBL6150769 | 0.80 | CA1 (0.45) | MAPTCA2CA12CA9CA1 | |
| Hydrochloric Acid SCHEMBL4824149 | 0.80 | GAA (0.42) | ALDH1A1MAPTKEAP1CA2CA12 | |
| SCHEMBL12201441 | 0.80 | LATS1 (0.49) | MAPTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL10341636 | 0.79 | ALDH1A1 (0.52) | ALDH1A1MAPTKEAP1CA2CA12 | |
| SCHEMBL6698064 | 0.79 | ALDH1A1 (0.52) | ALDH1A1MAPTCA2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9932445-B2 | Hygromorphic polymers and copolymers having humidity-driven motility | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2018-04-03 | — | — | US | claimed |
| US-20170260334-A1 | HYGROMORPHIC POLYMERS AND COPOLYMERS HAVING HUMIDITY-DRIVEN MOTILITY | GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE | 2017-09-14 | — | — | US | claimed |
| US-8022059-B2 | Indazole acrylic acid amide compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-09-20 | — | — | US | disclosed |
| US-20100256108-A1 | INDAZOLE ACRYLIC ACID AMIDE COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2010-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170260334-A1 | HYGROMORPHIC POLYMERS AND COPOLYMERS HAVING HUMIDITY-DRIVEN MOTILITY | DNAH12, PARG, PARN | ALDH1A1 2805/4885MAPT 1500/4885KEAP1 4786/4885 |
| US-20100256108-A1 | INDAZOLE ACRYLIC ACID AMIDE COMPOUND | KCNH2, KCNH3, KCNJ11 | ALDH1A1 711/4885MAPT 4800/4885KEAP1 1343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.