SCHEMBL12201441

SCHEMBL12201441

CS(=O)(=O)CCNc1ccncc1

nearest known ligand 0.49

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LATS1 O95835 1/20 0.49
F2 P00734 12/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
KMT2A Q03164 1/20 0.40
FDPS P14324 1/20 0.40
ADRA2B P18089 1/20 0.39
CTSD P07339 1/20 0.38
MAPT P10636 1/20 0.38
HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4749229 0.81 F2 (0.43) LATS1F2L3MBTL1KMT2AFDPS
SCHEMBL12311331 0.80 ALDH1A1 (0.52) L3MBTL1MAPT
SCHEMBL4818407 0.78 APP (0.43) KMT2AMAPT
Hydrochloric Acid SCHEMBL4824149 0.77 GAA (0.42) KMT2AMAPT
SCHEMBL6150769 0.77 CA1 (0.45) MAPT
SCHEMBL917421 0.74 FDPS (0.41) F2FDPSMAPT
SCHEMBL6151111 0.74 LMNA (0.39) L3MBTL1MAPTHPGD
SCHEMBL12122412 0.74 ALDH1A1 (0.47) LATS1L3MBTL1
SCHEMBL917554 0.74 FDPS (0.41) F2FDPSMAPT
SCHEMBL12097627 0.73 LATS1 (0.46) LATS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8034951-B2 Biological buffers with wide buffering ranges TPAT IP LLC 2011-10-11 US disclosed