Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | QPCT | Q16769 | 3/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SOD1 | P00441 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5189414 | 0.86 | CYP19A1 (0.60) | CYP19A1ALDH1A1KDM4ELMNAPOLB | |
| SCHEMBL6151236 | 0.81 | MAPT (0.41) | ALDH1A1POLBNPC1RAB9AMEN1 | |
| SCHEMBL7642996 | 0.80 | QPCT (0.56) | CYP19A1ALDH1A1KDM4ELMNAPOLB | |
| SCHEMBL5189230 | 0.78 | QPCT (0.69) | CYP19A1ALDH1A1KDM4EPOLBQPCT | |
| SCHEMBL5903400 | 0.78 | POLB (0.66) | CYP19A1ALDH1A1POLBQPCTMAOA | |
| SCHEMBL10581105 | 0.78 | ALDH1A1 (0.63) | CYP19A1ALDH1A1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL6151779 | 0.78 | CYP19A1 (0.50) | CYP19A1ALDH1A1KDM4ELMNAPOLB | |
| SCHEMBL5718326 | 0.77 | QPCT (0.56) | CYP19A1ALDH1A1KDM4ELMNAQPCT | |
| SCHEMBL9940645 | 0.76 | MAPT (0.54) | CYP19A1ALDH1A1KDM4ELMNAPOLB | |
| SCHEMBL5718416 | 0.76 | CYP19A1 (0.50) | CYP19A1ALDH1A1KDM4ELMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1018508-B1 | Cationic monobenzenic nitrophenylene diamines, their use for dyeing keratinic fibres, dye compositions containing them and dye processes | OREAL (FR) | 2005-05-04 | — | — | EP | disclosed |
| US-6464731-B1 | 1-(3-(4-AMINO-2-CHLORO-5-NITROPHENYLAMINO)PROPYL)-3-METHYL-3H -IMIDAZOL-1-IUM BROMIDE USED AS DIRECT HAIR DYES; SOLUBILITY AND PHOTOSTABILITY | L'OREAL S.A. (FR) | 2002-10-15 | — | — | US | disclosed |
| EP-1018508-A1 | Cationic monobenzenic nitrophenylene diamines, their use for dyeing keratinic fibres, dye compositions containing them and dye processes | L'OREAL (FR) | 2000-07-12 | — | — | EP | disclosed |