Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7664335 | 0.92 | MAPT (0.37) | MAPTKMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL6570543 | 0.87 | ALDH1A1 (0.39) | MAPTKMT2AALDH1A1HPGDPOLB | |
| SCHEMBL6152971 | 0.85 | HTR6 (0.38) | MAPTKMT2AALDH1A1GLAGAA | |
| SCHEMBL6572859 | 0.81 | ALDH1A1 (0.49) | MAPTKMT2AALDH1A1HPGDGLA | |
| SCHEMBL6151788 | 0.81 | CYP19A1 (0.53) | MAPTKMT2AALDH1A1POLBMAPK1 | |
| SCHEMBL7251857 | 0.80 | TMEM97 (0.37) | MAPTKMT2AALDH1A1GLAGAA | |
| SCHEMBL5718369 | 0.79 | TMEM97 (0.36) | MAPTKMT2AALDH1A1HPGDGLA | |
| SCHEMBL7664021 | 0.79 | HTR6 (0.34) | MAPTALDH1A1GLAGAAHTR6 | |
| SCHEMBL5718533 | 0.77 | MAPT (0.55) | MAPTKMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL5718310 | 0.77 | MAPT (0.38) | MAPTKMT2AALDH1A1GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1018508-B1 | Cationic monobenzenic nitrophenylene diamines, their use for dyeing keratinic fibres, dye compositions containing them and dye processes | OREAL (FR) | 2005-05-04 | — | — | EP | disclosed |
| EP-1018508-A1 | Cationic monobenzenic nitrophenylene diamines, their use for dyeing keratinic fibres, dye compositions containing them and dye processes | L'OREAL (FR) | 2000-07-12 | — | — | EP | disclosed |