⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700706 | 0.68 | — | — | |
| SCHEMBL8065648 | 0.67 | — | — | |
| SCHEMBL2405021 | 0.67 | — | — | |
| SCHEMBL28902208 | 0.64 | — | — | |
| SCHEMBL29014001 | 0.64 | — | — | |
| SCHEMBL2191847 | 0.62 | — | — | |
| SCHEMBL7855420 | 0.62 | LMNA (0.32) | — | |
| SCHEMBL9128877 | 0.61 | CASP6 (0.33) | — | |
| SCHEMBL10781386 | 0.61 | LMNA (0.33) | — | |
| SCHEMBL20211523 | 0.60 | ALDH1A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725826-B1 | IMPROVEMENTS RELATING TO CANCER THERAPY | CANCER RES CAMPAIGN TECH (GB) | 2005-01-26 | — | — | EP | claimed |
| EP-0725826-A1 | IMPROVEMENTS RELATING TO CANCER THERAPY | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1996-08-14 | — | — | EP | claimed |
| WO-1996014420-A1 | INDUCIBLE CELL ABLATION | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1996-05-17 | — | — | WO | claimed |
| WO-1995012678-A2 | IMPROVEMENTS RELATING TO CANCER THERAPY | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1995-05-11 | — | — | WO | claimed |
| EP-0725826-B1 | IMPROVEMENTS RELATING TO CANCER THERAPY | CANCER RES CAMPAIGN TECH (GB) | 2005-01-26 | — | — | EP | disclosed |
| EP-0725826-A1 | IMPROVEMENTS RELATING TO CANCER THERAPY | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1996-08-14 | — | — | EP | disclosed |
| WO-1996014420-A1 | INDUCIBLE CELL ABLATION | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1996-05-17 | — | — | WO | disclosed |
| WO-1995012678-A2 | IMPROVEMENTS RELATING TO CANCER THERAPY | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1995-05-11 | — | — | WO | disclosed |