Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CUL4A | Q13619 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 10/20 | 0.33 |
| ▸ | CA1 | P00915 | 6/20 | 0.33 |
| ▸ | CA9 | Q16790 | 5/20 | 0.33 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 2/20 | 0.31 |
| ▸ | CA7 | P43166 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27685146 | 0.84 | CA2 (0.37) | MAPTKDM4EHPGDHSD17B10CA2 | |
| SCHEMBL6152982 | 0.78 | MAPT (0.40) | MAPTKDM4EHPGDHSD17B10CUL4A | |
| Hydrochloric Acid SCHEMBL6610508 | 0.77 | MAPT (0.39) | MAPTKDM4EHPGDHSD17B10CUL4A | |
| SCHEMBL3212068 | 0.74 | CA2 (0.46) | MAPTKDM4EHPGDHSD17B10CA2 | |
| SCHEMBL27444582 | 0.68 | TSHR (0.37) | HSD17B10CA2CA1CA9CA12 | |
| SCHEMBL6150867 | 0.68 | CA2 (0.33) | KDM4ECA2CA1CA9CA12 | |
| SCHEMBL6733242 | 0.68 | CA2 (0.33) | KDM4ECA2CA1CA9CA12 | |
| SCHEMBL6610576 | 0.68 | KDM4E (0.37) | MAPTKDM4EHPGDHSD17B10CUL4A | |
| SCHEMBL3215200 | 0.68 | CA12 (0.41) | MAPTKDM4EHPGDHSD17B10CA2 | |
| SCHEMBL6910090 | 0.68 | MEN1 (0.40) | HPGDCA2CA1CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1598351-A1 | Substituted N-pyrimidinyl-N'-thienyl(amino)sulfonylureas as herbicides | Bayer CropScience AG (DE) | 2005-11-23 | — | — | EP | disclosed |
| EP-1206468-B1 | SUBSTITUTED THIENYL(AMINO)SULFONYLUREAS | BAYER CROPSCIENCE AG (DE) | 2005-06-15 | — | — | EP | disclosed |
| EP-1206468-A2 | SUBSTITUTED THIENYL(AMINO)SULFONYLUREAS | Bayer Aktiengesellschaft (DE) | 2002-05-22 | — | — | EP | disclosed |
| WO-2001010863-A2 | SUBSTITUTED THIENYL(AMINO)SULFONYLUREAS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-02-15 | — | — | WO | disclosed |