Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 15/20 | 0.33 |
| ▸ | CA1 | P00915 | 10/20 | 0.33 |
| ▸ | CA12 | O43570 | 7/20 | 0.33 |
| ▸ | CA7 | P43166 | 6/20 | 0.33 |
| ▸ | CA9 | Q16790 | 5/20 | 0.33 |
| ▸ | CA3 | P07451 | 2/20 | 0.33 |
| ▸ | CA6 | P23280 | 2/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.33 |
| ▸ | CA4 | P22748 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6150867 | 0.82 | CA2 (0.33) | CA2CA1CA12CA7CA9 | |
| SCHEMBL27501462 | 0.80 | GPR35 (0.32) | KDM4E | |
| SCHEMBL6152123 | 0.77 | CA2 (0.35) | CA2CA1CA12CA7CA9 | |
| SCHEMBL27444582 | 0.74 | TSHR (0.37) | CA2CA1CA12CA7CA9 | |
| SCHEMBL4894480 | 0.70 | CA2 (0.33) | CA2CA1CA12CA9 | |
| SCHEMBL3212068 | 0.70 | CA2 (0.46) | CA2CA1CA12CA9CA5A | |
| SCHEMBL27685146 | 0.70 | CA2 (0.37) | CA2CA1CA7CA9KDM4E | |
| SCHEMBL27392155 | 0.68 | CYP2C19 (0.41) | CA2CA1CA12CA7CA9 | |
| SCHEMBL7034372 | 0.68 | MAPT (0.47) | CA2CA1CA12CA9KDM4E | |
| SCHEMBL6151863 | 0.68 | MAPT (0.36) | CA2CA1CA12CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1195751-C | Thiophen sulfuryl compound | BAYER AG (DE) | 2005-04-06 | — | — | CN | disclosed |
| US-6686478-B2 | NOVEL INTERMEDIATES FOR THEIR PREPARATION; HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2004-02-03 | — | — | US | disclosed |
| US-20030171595-A1 | Thienylsulphonylamino(thio)carbonyl compounds | MULLER KLAUS-HELMUT (DE) | 2003-09-11 | — | — | US | disclosed |
| US-6566536-B2 | Herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2003-05-20 | — | — | US | disclosed |
| CN-1396163-A | Thiophen sulfuryl compound | BAYER AG (DE) | 2003-02-12 | — | — | CN | disclosed |
| US-20030004354-A1 | Thienylsulphonylamino(thio)carbonyl compounds | MULLER KLAUS-HELMUT (DE) | 2003-01-02 | — | — | US | disclosed |
| CN-1088705-C | Thiophenesulfonylamino carbonyl compounds | BAYER AG (DE) | 2002-08-07 | — | — | CN | disclosed |
| US-6383988-B1 | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-05-07 | — | — | US | disclosed |
| EP-0942908-B1 | THIENYLSULFONYLAMINO(THIO)CARBONYL COMPOUNDS | BAYER AG (DE) | 2002-02-13 | — | — | EP | disclosed |
| CN-1239960-A | Thiophenesulfonylamino carbonyl compounds | BAYER AG (DE) | 1999-12-29 | — | — | CN | disclosed |
| EP-0942908-A1 | THIENYLSULFONYLAMINO(THIO)CARBONYL COMPOUNDS | BAYER AG (DE) | 1999-09-22 | — | — | EP | disclosed |
| WO-1998024787-A1 | THIENYLSULFONYLAMINO(THIO)CARBONYL COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-06-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030171595-A1 | Thienylsulphonylamino(thio)carbonyl compounds | CBR3, CBR1, QSOX1 | CA2 124/4885CA1 860/4885CA12 1620/4885 |
| US-20030004354-A1 | Thienylsulphonylamino(thio)carbonyl compounds | CBR3, CBR1, QSOX1 | CA2 124/4885CA1 860/4885CA12 1620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.