SCHEMBL6152019

SCHEMBL6152019

CCCCCOc1ccc(-c2cc(-c3ccc(OCCCCC)cc3)c(C(=O)c3ccccc3)[nH]2)cc1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RARB P10826 3/20 0.50
GPR84 Q9NQS5 1/20 0.50
CTSV O60911 1/20 0.49
CTSL P07711 1/20 0.49
PTPN11 Q06124 3/20 0.48
GAA P10253 1/20 0.48
TP53 P04637 1/20 0.47
TSHR P16473 1/20 0.47
PLA2G4B P0C869 2/20 0.46
PPARA Q07869 1/20 0.45
NR1H4 Q96RI1 1/20 0.45
LMNA P02545 1/20 0.44
MAPK1 P28482 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13083610 0.86 GPR84 (0.54) RARBGPR84CTSVCTSLPTPN11
SCHEMBL6153219 0.83 CTSV (0.52) RARBGPR84CTSVCTSL
SCHEMBL6151728 0.79 RARB (0.54) RARBGPR84CTSVCTSL
SCHEMBL14306195 0.77 PPARA (0.71) RARBGAATP53TSHRPLA2G4B
SCHEMBL6153025 0.77 RARB (0.47) RARBGPR84CTSVCTSL
SCHEMBL21577818 0.77 CTSV (0.51) RARBGPR84CTSVCTSLPTPN11
SCHEMBL18774788 0.76 TP53 (0.73) RARBGAATP53TSHRPLA2G4B
SCHEMBL534753 0.76 TP53 (0.73) RARBGAATP53TSHRPLA2G4B
SCHEMBL11001285 0.76 TP53 (0.73) RARBGAATP53TSHRPLA2G4B
SCHEMBL6648277 0.76 TP53 (0.73) RARBGAATP53TSHRPLA2G4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1253151-B1 Pyrromethene metal complex and light emitting device composition and light emitting devices using the same TORAY INDUSTRIES (JP) 2005-01-12 EP disclosed
US-6805978-B2 COMPLEX CONTAINING DIKETOPYRROLO(3,4-C)PYRROLE COMPOUND TORAY INDUSTRIES, INC. (JP) 2004-10-19 US disclosed
US-20030082406-A1 Complex containing diketopyrrolo(3,4-c)pyrrole compound TORAY INDUSTRIES, INC. (JP) 2003-05-01 US disclosed
EP-1253151-A1 Pyrromethene metal complex and light emitting device composition and light emitting devices using the same TORAY INDUSTRIES, INC. (JP) 2002-10-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030082406-A1 Complex containing diketopyrrolo(3,4-c)pyrrole compound PPOX, CPNE4, TP53RK RARB 2079/4885GPR84 2529/4885CTSV 2058/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.